Feasibility of high temporal resolution breast DCE-MRI using compressed sensing theory
Feasibility of high temporal resolution breast DCE-MRI using compressed sensing theory
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DOI：
10.1118/1.3483094
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发表时间：
2010-09-01
期刊：
影响因子：
3.8
通讯作者：
Hu, Jiani
中科院分区：
文献类型：
--
作者：
Wang, Haoyu;Miao, Yanwei;Hu, Jiani
目的：探讨利用压缩传感理论进行高时间分辨率乳腺DCE-MRI的可行性方法：设计两个实验，探讨将基于参考图像的压缩传感（RICS）技术应用于乳腺DCE-MRI的可行性。第一个实验检查了RICS使用从完全采样的临床乳腺DCE-MRI数据中提取的欠采样数据集忠实地重建摄取曲线的能力。平均的方法和使用运动估计和运动补偿（ME/MC）的方法来获得参考图像，并评估其在减少运动相关的影响的功效。第二个实验，在体外体模的研究，测试的可行性RICS提高时间分辨率，而不降低的空间resolution.Results：对于摄取曲线重建实验，有一个高的相关性之间的摄取曲线重建从完全采样的数据通过傅立叶变换和从欠采样的数据通过RICS，表明它们之间的高度相似性。采用ME/MC方法的RICS和采用平均方法的RICS的平均Pearson相关系数分别为0.977 +/- 0.023和0.953 +/- 0.031。RICS平均法和RICS ME/MC法重建结果的比较表明，后者在减少运动相关影响方面上级前者。对于在体外实验中，完全采样的方法相比，RICS提高了时间分辨率的加速因子为10，而不降低空间resolution.Conclusions：初步研究表明，RICS的可行性重建忠实的摄取曲线，提高乳腺DCE-MRI的时间分辨率，而不降低空间分辨率。(C)2010年美国医学物理学家协会。[DOI：10.1118/1.3483094]
Purpose: To investigate the feasibility of high temporal resolution breast DCE-MRI using compressed sensing theory.Methods: Two experiments were designed to investigate the feasibility of using reference image based compressed sensing (RICS) technique in DCE-MRI of the breast. The first experiment examined the capability of RICS to faithfully reconstruct uptake curves using undersampled data sets extracted from fully sampled clinical breast DCE-MRI data. An average approach and an approach using motion estimation and motion compensation (ME/MC) were implemented to obtain reference images and to evaluate their efficacy in reducing motion related effects. The second experiment, an in vitro phantom study, tested the feasibility of RICS for improving temporal resolution without degrading the spatial resolution.Results: For the uptake-curve reconstruction experiment, there was a high correlation between uptake curves reconstructed from fully sampled data by Fourier transform and from undersampled data by RICS, indicating high similarity between them. The mean Pearson correlation coefficients for RICS with the ME/MC approach and RICS with the average approach were 0.977 +/- 0.023 and 0.953 +/- 0.031, respectively. The comparisons of final reconstruction results between RICS with the average approach and RICS with the ME/MC approach suggested that the latter was superior to the former in reducing motion related effects. For the in vitro experiment, compared to the fully sampled method, RICS improved the temporal resolution by an acceleration factor of 10 without degrading the spatial resolution.Conclusions: The preliminary study demonstrates the feasibility of RICS for faithfully reconstructing uptake curves and improving temporal resolution of breast DCE-MRI without degrading the spatial resolution. (C) 2010 American Association of Physicists in Medicine. [DOI: 10.1118/1.3483094]