The impact of environmental tobacco smoke on women's risk of dying from heart disease: a meta-analysis.
The impact of environmental tobacco smoke on women's risk of dying from heart disease: a meta-analysis.
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环境烟草烟雾对女性死于心脏病风险的影响：荟萃分析。
DOI：
10.1089/jwh.2004.13.888
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
Bastian,LoriA
中科院分区：
文献类型：
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作者：
Kaur,Suneet;Cohen,Adi;Dolor,Rowena;Coffman,CynthiaJ;Bastian,LoriA
目的：系统回顾和分析环境烟草烟雾(ETS)暴露与女性心脏病死亡风险的关系。方法：应用计算机检索英文文献MEDLINE(1966-2004-04)、中国期刊全文数据库(CINAHL)、心理信息数据库和部分研究文献。我们纳入了专门研究ETS与女性心脏病死亡率之间关系的研究，并有足够的对照和可恢复的风险估计。我们寻找队列研究或随机对照试验。研究由其中两位作者独立进行评估。最终选择了9项队列研究进行分析。我们使用随机效应模型估计了总的相对风险(RR)和相关的95%可信区间(95%CI)。结果：这些队列的平均随访期为6到39年。在不吸烟的女性中，暴露于ETS的女性与不吸烟的女性相比，死于心脏病的风险增加了15%(RR=1.15，95%可信区间1.03-1.28，p<；0.05)。结论：在不吸烟的女性中，暴露于二手烟增加了死于心脏病的风险。根据美国心脏协会制定的预防女性心血管疾病(CVD)的最新指南，我们建议女性减少或避免接触ETS。
Objective:To review systematically and analyze the association between environmental tobacco smoke (ETS) exposure and the risk of dying from heart disease in women.Methods:We searched the English-language literature using MEDLINE (1966–April 2004), CINAHL, PsychInfo, and bibliographies of selected studies. We included studies that specifically addressed the association of ETS and heart disease mortality in women and had adequate controls and retrievable risk estimates. We looked for either cohort studies or randomized controlled trials. Studies were evaluated independently by two of the authors. Nine cohort studies were finally selected for analysis. We estimated the summary relative risk (RR) and associated 95% confidence intervals (95% CI) using a random-effects model.Results:Mean follow-up periods for these cohorts ranged from 6 to 39 years. Among nonsmoking women, exposure to ETS was associated with a 15% increase in the risk of dying from heart disease compared with nonsmoking women not exposed to ETS (RR = 1.15, 95% CI 1.03-1.28,p< 0.05).Conclusions:Among nonsmoking women, exposure to passive smoke increases the risk of dying from heart disease. In accordance with the newly developed guidelines by the American Heart Association for prevention of cardiovascular disease (CVD) in women, we recommend counseling women on reducing or avoiding ETS exposure.