STRUCTURE OF CHROMOSOMES .I. MORPHOLOGICAL STUDIES OF SPIRAL STRUCTURE OF HUMAN SOMATIC CHROMOSOMES
STRUCTURE OF CHROMOSOMES .I. MORPHOLOGICAL STUDIES OF SPIRAL STRUCTURE OF HUMAN SOMATIC CHROMOSOMES
复制标题
DOI：
10.1007/bf02327721
复制
发表时间：
1968-01-01
期刊：
影响因子：
1.6
通讯作者：
OHNUKI, Y
中科院分区：
文献类型：
--
作者：
OHNUKI, Y
采用新发展的低渗处理技术，研究了人类体细胞染色体螺旋结构中的回旋数、卷曲方式和卷曲方向、着丝粒、次缢痕和端粒。主要研究结果如下：1.不同细胞的相似染色体中，回纹的数目很可能是恒定的; 2.线圈方向随机; 3.每个染色丝被认为是染色丝卷曲的一个单位; 4.着丝粒似乎是染色丝的区域性伸长部分，没有显示任何分化的结构; 5.次级缢痕处的染色丝通常表现为非卷曲或不太紧密卷曲的实体，和6.观察到两种不同类型的端粒结构，一种是尖端型，而另一种是圆端型（摘要见第424页）。
The number of gyres, mode, and direction of coils, centromere, secondary constriction, and telomere were studied in the human somatic chromosomes in terms of spiral structure, employing the newly developed technique involving a hypotonic treatment. Results obtained are: 1. the number of gyres is most probably constant in analogous chromosome from different cells; 2. the direction of coils is random; 3. each ehromatid is accepted as a unit of chromonema coiling; 4. the centromere seems to be a regionally elongated portion of the chromonema, without showing any differentiated structure; 5. chromonemata at secondary constrictions usually appear as uncoiled or less tightly coiled entities, and 6. two different types of the telomere structure were observed, one being a pointed-end type, while the other is a rounded-end type (Summary see p. 424).