Gut-associated Lymphoid Tissue in the Large Intestine of Calves. II. Electron Microscopy
Gut-associated Lymphoid Tissue in the Large Intestine of Calves. II. Electron Microscopy
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小牛大肠中的肠道相关淋巴组织。
DOI：
10.1177/030098588802500615
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发表时间：
1988
影响因子：
2.4
通讯作者：
N. Cheville
中科院分区：
文献类型：
--
作者：
E. Liebler;J. Pohlenz;N. Cheville
3只无菌犊牛（3、6和7日龄）大肠淋巴组织的扫描电镜显示了两种不同的单位：固有结节和淋巴腺复合物（LGC）。固有结节主要在固有层有淋巴样组织，被明显的滤泡相关上皮覆盖，缺乏杯状细胞；结节被宽隐窝包围，隐窝向管腔一侧排列着卵泡相关上皮。淋巴腺复合体粘膜下层有淋巴样卵泡；上皮性憩室穿过粘膜肌层延伸至淋巴样结节。在淋巴腺复合体的中心，淋巴组织的突起被明显的滤泡相关上皮覆盖。透射电镜观察发现犊牛小肠中存在与M细胞相容的细胞，同时具有肠吸收细胞和M细胞的特性。固有结节和淋巴腺复合体的滤泡相关上皮仅在细胞类型的相对频率上不同。
Scanning electron microscopy of lymphoid tissue in the large intestine of three germfree calves (age 3, 6, and 7 days) revealed two different units: propria nodules and lymphoglandular complexes (LGC). Propria nodules had lymphoid tissue predominantly in lamina propria and were covered by distinct follicle-associated epithelium which lacked goblet cells; nodules were surrounded by wide crypts, which were also lined by follicle-associated epithelium towards the luminal side. Lymphoglandular complexes had lymphoid follicles in the tunica submucosa; epithelial diverticulae extended through the muscularis mucosae branching into the lymphoid nodule. In centers of lymphoglandular complexes, protrusions of lymphoid tissue were covered with distinct follicle-associated epithelium. By transmission electron microscopy cells compatible with M cells in the small intestine of calves and cells with characteristics of both enteroabsorptive and M cells were found. Follicle-associated epithelium of propria nodules and lymphoglandular complexes differed only in the relative frequency of cell types.