Growth of Infants with Intestinal Failure or Feeding Intolerance Does Not Follow Standard Growth Curves
Growth of Infants with Intestinal Failure or Feeding Intolerance Does Not Follow Standard Growth Curves
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DOI：
10.1155/2017/8052606
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发表时间：
2017-01-01
影响因子：
2.2
通讯作者：
Moore, Carolyn E.
中科院分区：
文献类型：
--
作者：
Morton, Danielle L.;Hawthorne, Keli M.;Moore, Carolyn E.
客观的。患有肠道衰竭或喂养不耐受的婴儿营养受损，并且面临宫外生长受限的风险。该研究的目的是评估患有肠道衰竭和喂养不耐受的婴儿在出生后头三个月的生长速度，并确定出生时和月经后 40 周 (PMA) 时的生长百分位数。方法。德克萨斯儿童医院肠道康复小组于 2012 年 4 月至 2014 年 10 月期间对婴儿进行了图表审查。计算了每周的体重、身长和头围生长速度。将生长数据与奥尔森生长曲线进行比较以确定准确的百分位。结果。来自婴儿（n = 164）的数据显示，3个月大婴儿的平均生长速度（体重增加，19.97克/天；身长，0.81厘米/周；头围，0.52厘米/周）存在波动，均低于预期标准。出院或死亡时，平均生长速度进一步下降（身长，0.69 厘米/周；头围，0.45 厘米/周），但体重略有增加（体重，20.56 克/天）。从出生到 40 周 PMA，体重、身长和头围百分位数显着下降 (P < 0.001)。结论。患有肠衰竭或喂养不耐受的婴儿的生长不遵循标准生长曲线。
Objective. Infants with intestinal failure or feeding intolerance are nutritionally compromised and are at risk for extrauterine growth restriction. The aim of the study was to evaluate growth velocities of infants with intestinal failure and feeding intolerance for the first three months of age and to determine growth percentiles at birth and at 40-week postmenstrual age (PMA). Methods. A chart review of infants followed by the Texas Children's Hospital Intestinal Rehabilitation Team was conducted from April 2012 to October 2014. Weekly weight, length, and head circumference growth velocities were calculated. Growth data were compared to Olsen growth curves to determine exact percentiles. Results. Data from infants (n = 164) revealed that average growth velocities of 3-month-old infants (weight gain, 19.97 g/d; length, 0.81 cm/week; head circumference, 0.52 cm/week) fluctuated and all were below expected norms. At discharge or death, average growth velocities had further decreased (length, 0.69 cm/week; head circumference, 0.45 cm/week) except for weight, which showed a slight increase (weight, 20.56 g/d). Weight, length, and head circumference percentiles significantly decreased from birth to 40-week PMA (P < 0.001). Conclusions. Growth of infants with intestinal failure or feeding intolerance did not follow standard growth curves.