The London Classification of gastrointestinal neuromuscular pathology: report on behalf of the Gastro 2009 International Working Group
The London Classification of gastrointestinal neuromuscular pathology: report on behalf of the Gastro 2009 International Working Group
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DOI：
10.1136/gut.2009.200444
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发表时间：
2010-07-01
期刊：
影响因子：
24.5
通讯作者：
Wedel, Thilo
中科院分区：
文献类型：
--
作者：
Knowles, Charles H.;De Giorgio, Roberto;Wedel, Thilo
目的一个国际工作组(IWG)最近提出了成人和儿童胃肠道神经肌肉病理学的组织病理学技术和报告指南。这些内容涉及普通病理学家重要但相对被忽视的组织病理学实践领域，包括吸引性直肠活检和全层肠道组织。对此类组织材料的适应症、组织安全获取、组织学技术、报告和转诊提出了建议。设计由IWG进行的协商过程，并遵循已建立的指南决策组方法学。结果和结论本报告根据现有指南中定义的组织病理学标准，提出了一种当代的结构化胃肠神经肌肉病理学分类。为了确认它的起源，并在2009年世界胃肠病学大会上首次在伦敦提出，这一分类被命名为“伦敦分类”。这种分类的实施应该允许一些诊断标准化，但随着新数据的出现，必须将其视为未来修改的起点。
Objective Guidelines on histopathological techniques and reporting for adult and paediatric gastrointestinal neuromuscular pathology have been produced recently by an international working group (IWG). These addressed the important but relatively neglected areas of histopathological practice of the general pathologist, including suction rectal biopsy and full-thickness intestinal tissue. Recommendations were presented for the indications, safe acquisition of tissue, histological techniques, reporting and referral of such histological material.Design Consensual processes undertaken by the IWG and following established guideline decision group methodologies.Results and conclusion This report presents a contemporary and structured classification of gastrointestinal neuromuscular pathology based on defined histopathological criteria derived from the existing guidelines. In recognition of its origins and first presentation in London at the World Congress of Gastroenterology 2009, this has been named 'The London Classification'. The implementation of this classification should allow some diagnostic standardisation, but should necessarily be viewed as a starting point for future modification as new data become available.