Dihydroflavonols from Lannea coromandelica

Dihydroflavonols from Lannea coromandelica
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DOI:
10.1016/s0031-9422(00)00048-0
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发表时间:
2000-08-01
期刊:
影响因子:
3.8
通讯作者:
Tahara, S
Tahara, S
中科院分区:
生物学2区
文献类型:
--
作者:
Islam, MT;Tahara, S

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从山榄(Lannea coromandelica)茎皮中分离得到两个黄酮醇类化合物:(2 R,3S)-(+)-3 ',5-二羟基-4',7-二甲氧基二氢黄酮醇和(2 R,3R)-(+)-4 ',5,7-三甲氧基二氢黄酮醇。与已知的(2 R,3R)-(+)-4 ′,7-二-O-甲基二氢槲皮素、(2 R,3R)-(+)-4 ′,7-二-O-甲基二氢山奈酚和(2 R,3R)-(+)-4 ′-O-甲基二氢槲皮素一起沿着。其中(2 R,3S)-(+)-3 ',5-二羟基-4',7-二甲氧基二氢黄酮醇为罕见的顺式异构体。所有化合物的结构均经2D NMR和CD分析确证。(C)2000爱思唯尔科技有限公司版权所有。
The dihydroflavonols, (2R,3S)-(+)-3',5-dihydroxy-4',7-dimethoxydihydroflavonol and (2R,3R)-(+)-4',5,7-trimethoxydihydroflavonol were isolated from the stem bark of Lannea coromandelica. along with the known (2R,3R)-(+)-4',7-di-O-methyldihydroquercetin, (2R,3R)-(+)-4',7-di-O-methyldihydrokaempferol and (2R,3R)-(+)-4'-O-methyldihydroquercetin. All five compounds were isolated for the first time from the genus Lannea; furthermore, (2R,3S)-(+)-3',5-dihydroxy-4',7-dimethoxydihydroflavonol, was a rare cis-type isomer. The structures of all compounds were elucidated by spectroscopic methods including 2D NMR and CD analysis. (C) 2000 Elsevier Science Ltd. All rights reserved.