Perinatal maternal depression in rural South Africa: Child outcomes over the first two years

Perinatal maternal depression in rural South Africa: Child outcomes over the first two years
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DOI:
10.1016/j.jad.2019.01.019
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发表时间:
2019-03-15
影响因子:
6.6
通讯作者:
Rotheram-Borus, Mary Jane
Rotheram-Borus, Mary Jane
中科院分区:
医学2区
文献类型:
--
作者:
Christodoulou, Joan;Le Roux, Karl;Rotheram-Borus, Mary Jane

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目的:检测南非农村地区有围产期抑郁情绪的母亲随时间的儿童结局。方法:在南非东开普省的OR Tambo区连续分娩的470名具有代表性的样本(470/493)中,在接下来的两年中在5个点上重新评估:85%在出生后3个月,92%在出生后6个月,88%在出生后9个月,91%在出生后12个月,88%在出生后2年。结果:与无抑郁情绪的母亲相比,有抑郁情绪的母亲明显更少地与孩子的父亲或岳父母生活在一起(23%比35%),家庭收入超过2000 ZAR(154美元)(31%比51%),怀孕前(19%比9%)和怀孕期间(32%比20%)经历过IPV。在年龄、教育程度、初产妇、艾滋病毒状况(29%血清阳性)或饮酒方面没有差异。有和没有围产期抑郁情绪的母亲出生后24个月的生长发育迟缓和运动和语言里程碑是相似的。结论:尽管经济和伴侣困难与围产期抑郁情绪有关,但在南非农村,有抑郁情绪的母亲和没有抑郁情绪的母亲的婴儿结局相似。]
Aims: To examine child outcomes over time among mothers with perinatally depressed mood in rural South Africa (SA).Methods: A representative sample of consecutive births (470/493) in the OR Tambo District of the Eastern Cape of South Africa (SA) were recruited and were reassessed at five points over the course of the next two years: 85% were reassessed at 3 months, 92% at 6 months, 88% at 9 months, 91% at 12 months, and 88% at 2 years post-birth. Over time, the children of mothers with perinatally depressed mood (16%) were compared to children of mothers without depressed mood using multiple linear and logistic regressions.Results: Mothers with perinatal depressed mood are significantly less likely to live with the child's father or their in-laws (23% vs 35%), have household incomes above 2000 ZAR (154 USD) (31% vs 51%), and significantly more likely to have experienced IPV prior (19% vs 9%) and during (32% vs 20%) pregnancy compared to mothers without depressed mood. There are no differences in age, education, primipara, HIV status (29% seropositive), or alcohol use. Growth and developmental delays and motor and speech milestones through 24 months post-birth are similar for mothers with and without perinatal depressed mood.Conclusions: Despite increased economic and partner difficulties associated with perinatal depressed mood, infant outcomes are similar in mothers with and without depressed mood in rural South Africa.]