A pilot randomized controlled study on the effect of laser photocoagulation of confluent soft macular drusen
A pilot randomized controlled study on the effect of laser photocoagulation of confluent soft macular drusen
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DOI：
10.1016/s0161-6420(97)30261-9
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发表时间：
1997-04-01
期刊：
影响因子：
13.7
通讯作者：
Brown, BW
中科院分区：
文献类型：
--
作者：
Little, HL;Showman, JM;Brown, BW
目的：方法：对27例年龄46 ~ 81岁，视力正常的对称性黄斑病变患者，随机对其中一只眼进行光凝治疗，另一只眼作为对照，观察光凝治疗玻璃疣对视力及视网膜下新生血管膜进展的影响结果：12例患者治疗眼最终视力提高或对照眼视力下降，13例患者治疗眼最终视力提高或对照眼视力下降，2例患者治疗眼最终视力下降（P < 0.006）。结论：融合性黄斑玻璃膜疣的激光光凝治疗可以改善长期视力预后。
Purpose: The authors determined the effect of photocoagulation of drusen on visual acuity and progression to subretinal neovascular membranes (SRNV).Methods: One of paired eyes was randomized to photocoagulation with other eye to control in 27 patients having symmetrical maculopathy and visual acuities, aged 46 to 81 years (mean, 69.7 years); follow-up 1 to 6 years (mean, 3.2 years).Results: Final visual acuity was improved in treated eye or decreased in control eye in 12 patients, equal in 13 patients, and decreased in treated eye in 2 patients (P < 0.006). Progression to SRNV was less with treatment.Conclusion: Laser photocoagulation of confluent soft macular drusen may improve long-term visual prognosis.