Cancer incidence in Florida professional firefighters, 1981 to 1999

Cancer incidence in Florida professional firefighters, 1981 to 1999
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DOI:
10.1097/01.jom.0000235862.12518.04
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发表时间:
2006-09-01
影响因子:
3.2
通讯作者:
Gerace, Terence A.
Gerace, Terence A.
中科院分区:
医学4区
文献类型:
--
作者:
Ma, Fangchao;Fleming, Lora E.;Gerace, Terence A.

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目的:本研究的目的是检查与消防相关的癌症风险。方法:使用标准化发病率分析(SIR)来确定消防员与佛罗里达州普通人群相比的相对癌症风险。结果:在 34,796 名男性(413,022 人年)和 2,017 名女性(18,843 人年)消防员中,发现了 970 名男性和 52 名女性癌症病例。男性消防员的膀胱癌(SIR = 1.29;95% 置信区间 = 1.01-1.62)、睾丸癌(1.60;1.20-2.09)和甲状腺癌(1.77;1.08-2.73)的发病率显着增加。女性消防员的总体癌症(1.63;1.22-2.14)、宫颈癌(5.24;2.93-8.65)、甲状腺癌(3.97;1.45-8.65)和霍奇金病(6.25;1.26-18.26)的发病率显着增加。结论:消防可能与男性和女性特定部位癌症的风险增加有关,包括女性消防员整体癌症风险的增加。
Objective: The objective of this study was to examine the cancer risk associated with firefighting. Methods: Standardized incidence ratio analysis (SIR) was used to determine the relative cancer risk for firefighters as compared with the Florida general population. Results: Among 34,796 mate (413,022 person-years) and 2,017 female (18,843 person-years) firefighters, 970 male and 52 female cases of cancer were identified. Male firefighters had significantly increased incidence rates of bladder (SIR = 1.29; 95% confidence interval = 1.01-1.62), testicular (1.60; 1.20-2.09), and thyroid cancers (1.77; 1.08-2.73). Female firefighters had significantly increased incidence rates Of overall cancer (1.63; 1.22-2.14), cervical (5.24; 2.93-8.65), and thyroid cancer (3.97; 1.45-8.65) and Hodgkin disease (6.25; 1.26-18.26). Conclusions: Firefighting may be associated with an increased risk of selected site-specific cancers in males and females, including an overall increased cancer risk in female firefighters.