Quantitative regression analysis of the cutaneous vascular territories in a rat model
Quantitative regression analysis of the cutaneous vascular territories in a rat model
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DOI：
10.1007/s00276-011-0809-7
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发表时间：
2011-04
影响因子：
1.4
通讯作者：
Y. Tao;Siwang Hu;Koonhei W. Lui;Shaohe Chen;M. Tang;Shixin Chen
中科院分区：
文献类型：
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作者：
Y. Tao;Siwang Hu;Koonhei W. Lui;Shaohe Chen;M. Tang;Shixin Chen
研究背景大鼠皮瓣模型已广泛应用于实验性皮瓣存活研究；然而，其中大部分都是定性研究。本研究的目的是探讨皮肤动脉直径与其所供应的皮肤面积之间的定量关系，并探讨影响这种关系的因素。方法对30只大鼠注射氧化铅和明胶，并进行X线摄影。对皮肤动脉的直径和供血面积进行计算机成像，以研究动脉直径与其灌注面积之间的数学关系。使用Adobe Photoshop制作血管图，并使用Scion Image和SPSS软件进行分析。结果血管平均直径0.53±0.12mm，周长18.74±4.84cm，血管密度391.31±76.58灰度值/像素cm，血管面积22.32±10.04cm2，供应体积4.88 ± 3.02 cm3。血管域的直径和周长以及血管域的面积和体积之间存在正相关关系。线性回归方程 wasy= 32.44x+ 1.23 [y: 营养区周长 (cm),x: 皮动脉直径 (mm)],y= 72.70x−15.93 [y: 供应面积 (cm2),x: 皮动脉直径 (mm)] andy= 20.36x−5.83 [y: 供应体积 (cm3),x: 皮动脉直径 (mm)],结论基于该数据，推测可以通过皮动脉的直径和分布模式来计算可靠的皮瓣尺寸。在直径相同的情况下，分支动脉供血的皮瓣面积比轴动脉供血的面积大。
BackgroundThe rat skin flap model has been widely used in experimental flap survival studies; however, most of these have been qualitative studies. The purpose of this study was to investigate the quantitative relationship between the diameter of a cutaneous artery and the area of skin that it supplies, and also to explore the factors that influence this relationship.MethodsThirty rats were injected with lead oxide and gelatin and then radiographed. Computer imaging of the diameter and the area of blood supply of the cutaneous artery were made to investigate the mathematical relationship between the arterial diameter and its perfusion area. Angiograms were assembled using Adobe Photoshop and analyzed with Scion Image and SPSS software.ResultsThe blood vessels had an average diameter of 0.53 ± 0.12 mm, perimeter of 18.74 ± 4.84 cm, vascular density of 391.31 ± 76.58 gray value/pixel cm, vascular territory of 22.32 ± 10.04 cm2and supplying volume of 4.88 ± 3.02 cm3. There was a positive correlation between the diameter and the perimeter of the vascular territory, and the area and volume of the vascular territory. The linear regression equation wasy= 32.44x+ 1.23 [y: nutrition region perimeter (cm),x: cutaneous artery diameter (mm)],y= 72.70x−15.93 [y: supplying area (cm2),x: cutaneous artery diameter (mm)] andy= 20.36x−5.83 [y: supplying volume (cm3),x: cutaneous artery diameter (mm)], respectively.ConclusionsBased on this data, it is postulated that the size of reliable skin flaps can be calculated by the diameter and the distribution patterns of the cutaneous artery. With the same diameter, the area of the flap supplied by branch-style artery is larger than the one supplied by the axial artery.