COVID-19: Structural Considerations for Virus Pathogenesis, Therapeutic Strategies and Vaccine Design in the Novel SARS-CoV-2 Variants Era.
COVID-19: Structural Considerations for Virus Pathogenesis, Therapeutic Strategies and Vaccine Design in the Novel SARS-CoV-2 Variants Era.
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DOI:
10.1007/s12033-021-00353-4
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发表时间:
2021-10
影响因子:
2.6
通讯作者:
Volkan E
中科院分区:
文献类型:
--
作者:
Volkan E
COVID-19 pandemic caused by SARS-CoV-2 globally impacted the humanity causing tragic outcomes; costing millions of lives, destroying economies and demolishing public health infrastructures. The emergence of vaccines using various ingenious approaches in less than a year was deemed the light at the end of the tunnel. However, recent emergence of variants of SARS-CoV-2 in several parts of the world revealed that another hurdle is ahead in the fight against COVID-19. This review will highlight how SARS-CoV-2 mutations, creating different virus variants could potentially impact virus pathogenesis as well as different therapy approaches and vaccine design.
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DOI:
10.1016/s2468-2667(21)00055-4
发表时间:
2021-05
期刊:
The Lancet. Public health
影响因子:
--
作者:
Graham MS;Sudre CH;May A;Antonelli M;Murray B;Varsavsky T;Kläser K;Canas LS;Molteni E;Modat M;Drew DA;Nguyen LH;Polidori L;Selvachandran S;Hu C;Capdevila J;COVID-19 Genomics UK (COG-UK) Consortium;Hammers A;Chan AT;Wolf J;Spector TD;Steves CJ;Ourselin S
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DOI:
10.1126/science.abg3055
发表时间:
2021-04-09
期刊:
Science (New York, N.Y.)
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Edmunds WJ
DOI:
10.1038/nrmicro.2016.81
发表时间:
2016-08
期刊:
Nature reviews. Microbiology
影响因子:
--
作者:
de Wit E;van Doremalen N;Falzarano D;Munster VJ
通讯作者:
Munster VJ
DOI:
10.1186/s13054-021-03572-y
发表时间:
2021-04-12
期刊:
Critical care (London, England)
影响因子:
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作者:
Castelli GP;Pognani C;Sozzi C;Franchini M;Vivona L
通讯作者:
Vivona L
影响因子:
16.8
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通讯作者:
Acharya P