PERIPHERAL ODONTOGENIC FIBROMA
PERIPHERAL ODONTOGENIC FIBROMA
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DOI：
10.1016/0030-4220(94)90064-7
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发表时间：
1994-09-01
影响因子：
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通讯作者：
WYSOCKI, GP
中科院分区：
文献类型：
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作者：
DALEY, TD;WYSOCKI, GP
周围型牙源性纤维瘤的特点是纤维性或纤维粘液性增生，其中含有不同数量的牙源性或推测为牙源性上皮。它被认为是一种罕见的牙龈肿瘤，由于在大多数报道的病例中缺乏后续信息，具有未知的生物学行为。这项研究的临床数据表明，这种病变比以前报道的更常见，而且复发率很高。光镜和电子显微镜数据显示了相对广泛的上皮和间充质成分，包括一种罕见的颗粒细胞类型。因为它的诊断需要上皮和间充质成分的存在，所以从逻辑上讲，该病变被归类为上皮/间充质混合型牙源性肿瘤，而不是单纯的间叶性肿瘤。
The peripheral odontogenic fibroma is characterized by a fibrous or fibromyxomatous proliferation that contains varying amounts of odontogenic or presumed odontogenic epithelium. It has been considered a rare gingival neoplasm that, because of a lack of follow-up information in most reported cases, has had an unknown biologic behavior. Clinical data from this study indicate that the lesion is more common than previously reported and that it has a significant recurrence rate. Light and electron microscopic data reveal a relatively broad spectrum of epithelial and mesenchymal components, including a rare granular cell type. Because the presence of both epithelial and mesenchymal elements are required for its diagnosis, the lesion is logically classified as a mixed epithelial/mesenchymal odontogenic tumor, rather than a purely mesenchymal tumor.