DNA fuel for free-running nanomachines

DNA fuel for free-running nanomachines
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DOI:
10.1103/physrevlett.90.118102
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发表时间:
2003-03-21
影响因子:
8.6
通讯作者:
Simmel, FC
Simmel, FC
中科院分区:
物理与天体物理1区
文献类型:
--
作者:
Turberfield, AJ;Mitchell, JC;Simmel, FC

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我们描述动力学控制的DNA杂交:环复合物被用来抑制互补的寡核苷酸的杂交,合理设计的DNA催化剂被证明是有效的,在促进其杂交。这是利用DNA作为燃料来驱动自由运行的人工分子机器的策略的基础。
We describe kinetic control of DNA hybridization: loop complexes are used to inhibit the hybridization of complementary oligonucleotides; rationally designed DNA catalysts are shown to be effective in promoting their hybridization. This is the basis of a strategy for using DNA as a fuel to drive free-running artificial molecular machines.