Frequent vegetable consumption is inversely associated with hypertension among indigenous Africans.
Frequent vegetable consumption is inversely associated with hypertension among indigenous Africans.
复制标题
非洲土著人经常食用蔬菜与高血压呈负相关。
DOI：
10.1093/eurjpc/zwac208
复制
发表时间：
2022
影响因子：
8.3
通讯作者：
Ogb
中科院分区：
文献类型：
--
作者：
Akpa,OnojaMatthew;Okekunle,AkinkunmiPaul;Asowata,OsahonJeffery;Chikowore,Tinashe;Mohamed,ShukriF;Sarfo,Fred;Akinyemi,Rufus;Akpalu,Albert;Wahab,Kolawole;Obiako,Reginald;Komolafe,Morenikeji;Owolabi,Lukman;Osaigbovo,GodwinO;Ogb
在撒哈拉以南非洲地区，蔬菜消费与高血压发生之间的关系仍然很差。本研究评估了蔬菜消费与土著Africans.Methods和resultsWe高血压发病率的几率的关联协调数据之前的蔬菜消费和高血压的发生（定义为以下条件之一;收缩压≥140或舒张压≥90 毫米汞柱或以前的诊断或使用抗高血压药物）从16 445名参与者在五个非洲国家（尼日利亚、南非、肯尼亚、加纳和布基纳法索）参与中风调查研究和教育网络以及非洲Wits-INDEPTH基因组研究伙伴关系。蔬菜消费量（每周食用量）被归类为“低”（<6）。“中等”（6-11）、“足够”（12-29）和“高”（≥30）。采用Logistic回归分析，以蔬菜摄入量低为参照，调整性别、年龄、心血管疾病家族史、教育、吸烟、饮酒、缺乏运动、体重指数、糖尿病和血脂异常等因素，估计高血压的OR值和95%可信区间（P < 0.05）。参与者的平均年龄为53.0（± 10.7）岁，7552（45.9%）人为男性，7070（42.9%）人患有高血压。此外，6672名（40.6%）参与者蔬菜消费量“低”，1758名（10.7%）蔬菜消费量“高”。蔬菜消费分布对高血压的多变量校正OR（以“低”消费量为参照）的平均消费量为1.03（95%CI：0.95，1.12）为“中度”消费; 0.80（0.73，0.88）对于“顺从”，和0.81（0.72，0.92）对于“高”消耗，趋势P <0.0001。结论每周至少食用12份蔬菜的土著非洲人不太可能被发现患有高血压，尤其是在男性和年轻人中。
AimsThe relationship between vegetable consumption and hypertension occurrence remains poorly characterized in sub-Saharan Africa. This study assessed the association of vegetable consumption with odds of hypertension among indigenous Africans.Methods and resultsWe harmonized data on prior vegetable consumption and hypertension occurrence (defined as one of the following conditions; systolic blood pressure ≥140 or diastolic blood pressure ≥90 mmHg or previous diagnosis or use of antihypertensive medications) from 16 445 participants across five African countries (Nigeria, South Africa, Kenya, Ghana and Burkina Faso) in the Stroke Investigative Research and Educational Network and Africa Wits-INDEPTH partnership for Genomic studies. Vegetable consumption (in servings/week) was classified as ‘low’ (<6). ‘moderate’ (6–11), ‘sufficient’ (12–29), and ‘high’ (≥30). Odds ratios (ORs) and 95% confidence interval (CI) of hypertension were estimated by categories of vegetable consumption (using ‘low’ consumption as reference), adjusting for sex, age in years, family history of cardiovascular diseases, education, smoking, alcohol use, physical inactivity, body mass index, diabetes mellitus and dyslipidaemia using logistic regressions atP< 0.05. The mean age of participants was 53.0 ( ± 10.7) years, and 7552 (45.9%) were males, whereas 7070 (42.9%) had hypertension. In addition, 6672(40.6%) participants had ‘low’ vegetable consumption, and 1758(10.7%) had ‘high’ vegetable consumption. Multivariable-adjusted OR for hypertension by distribution of vegetable consumption (using ‘low’ consumption as reference) were 1.03 (95% CI: 0.95, 1.12) for ‘moderate’ consumption; 0.80 (0.73, 0.88) for ‘sufficient’, and 0.81 (0.72, 0.92) for ‘high’ consumption,P-for-trend <0.0001.ConclusionIndigenous Africans who consumed at least 12 servings of vegetables per week were less likely to be found hypertensive, particularly among males and young adults.