De novo chromosome-length assembly of the mule deer (Odocoileus hemionus) genome.
De novo chromosome-length assembly of the mule deer (Odocoileus hemionus) genome.
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DOI：
10.46471/gigabyte.34
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Frandsen PB
中科院分区：
文献类型：
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作者：
Lamb S;Taylor AM;Hughes TA;McMillan BR;Larsen RT;Khan R;Weisz D;Dudchenko O;Aiden EL;Edelman NB;Frandsen PB
黑尾鹿（Odocoileus hemionus）是一种有蹄类动物，分布于加拿大西部至墨西哥中部。骡鹿是许多食肉动物的重要食物来源，数量相对丰富，通常会进行广泛的迁徙运动。更清楚地了解黑尾鹿基因组可以提高我们对其种群遗传学，运动和人口统计学历史的了解，有助于保护工作。它们庞大的人口规模，连续分布和栖息地的多样性使黑尾鹿成为人口基因组学研究的优秀候选人;然而，目前该物种的基因组资源很少。在这里，我们序列和组装的黑尾鹿基因组到一个高度连续的染色体长度大会在未来的研究中使用长读测序和Hi-C技术。我们还提供了一个基因组注释和比较的骡鹿和白尾鹿的人口历史，使用成对顺序马尔可夫合并模型。我们希望这个组件是一个宝贵的资源，在继续研究和保护黑尾鹿。
The mule deer (Odocoileus hemionus) is an ungulate species that is distributed in a range from western Canada to central Mexico. Mule deer are an essential source of food for many predators, are relatively abundant, and commonly make broad migration movements. A clearer understanding of the mule deer genome can improve our knowledge of its population genetics, movements, and demographic history, aiding in conservation efforts. Their large population size, continuous distribution, and diversity of habitat make mule deer excellent candidates for population genomics studies; however, few genomic resources are currently available for this species. Here, we sequence and assemble the mule deer genome into a highly contiguous chromosome-length assembly for use in future research using long-read sequencing and Hi-C technologies. We also provide a genome annotation and compare demographic histories of the mule deer and white-tailed deer using the pairwise sequentially Markovian coalescent model. We expect this assembly to be a valuable resource in the continued study and conservation of mule deer.