Bone-Demineralized bone-Bone Grafts for Ligament Reconstruction
Bone-Demineralized bone-Bone Grafts for Ligament Reconstruction
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DOI：
10.1299/jbse.2.23
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发表时间：
2007
影响因子：
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通讯作者：
Takeki Yamada;Y. Koyama;T. Kawai;T. Muneta;K. Takakuda
中科院分区：
文献类型：
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作者：
Takeki Yamada;Y. Koyama;T. Kawai;T. Muneta;K. Takakuda
在兔模型中研究了使用新型脱矿骨移植物的韧带重建。通过仅对长骨样本的中心部分进行脱矿，移植物具有骨-肌腱-骨移植物的结构，并且在弯曲时具有灵活性。制备了股骨条型、胫骨棒型和掌骨管型移植物，通过拉伸试验和动物实验评价了它们重建内侧副韧带（MCL）和前交叉韧带（ACL）的性能。条形和棒状移植物的最大强度约为MCL的一半，管状移植物的最大强度约为ACL的一半。条型移植物成活率约50%，棒状移植物成活率约60%。重建ACL时，条型移植物成活率为0%，棒型移植物成活率为10%，管状移植物成活率为50%，缝线加固管状移植物成活率为60%。条状和棒状移植物可用于MCL重建，管状移植物可用于ACL重建，并适当加强。
Ligament reconstruction with the use of novel demineralized bone grafts was investigated in a rabbit model. By demineralizing only the central portions of the long bone samples, the grafts had a configuration of the bone-tendon-bone graft and were flexible in bending. Strip type grafts made from femur, stick type grafts from tibia, and tube type grafts from metacarpal bones were prepared and their performances were evaluated by tensile testing and animal experiments for medial collateral ligament (MCL) and anterior cruciate ligament (ACL) reconstruction. The maximum strength of the strip and stick type grafts were about half of that of MCL, and that of tube type grafts was also about half of that of ACL. The survival rate of strip type grafts in MCL reconstruction was about 50%, and that of stick type was about 60%. In ACL reconstruction, the survival rate of strip type grafts was 0%, that of stick type was 10%, whereas that of tube type grafts was 50%, and that of tube type grafts reinforced with suture was 60%. The strip and stick type grafts might be useful for MCL reconstruction and the tube type grafts might be available for ACL reconstruction with suitable reinforcements.