Simultaneous noninvasive recording of electrocardiogram and skin sympathetic nerve activity (neuECG)

Simultaneous noninvasive recording of electrocardiogram and skin sympathetic nerve activity (neuECG)
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DOI:
10.1038/s41596-020-0316-6
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发表时间:
2020-04-20
期刊:
影响因子:
14.8
通讯作者:
Chen, Peng-Sheng
Chen, Peng-Sheng
中科院分区:
生物学1区
文献类型:
--
作者:
Kusayama, Takashi;Wong, Johnson;Chen, Peng-Sheng

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neuECG是心电图和皮肤交感神经活动的同时无创记录,因此可以在长时间内直接记录交感神经活动,而不需要侵入性程序。neuECG是心电图和皮肤交感神经活动(SKNA)的同时无创记录,直接记录交感神经活动。它可用于测量健康受试者和患有非心血管疾病的受试者的交感神经张力。可以在皮肤表面上测量的电活动源自心脏、肌肉或神经结构。由于神经活动的频率成分福尔斯落在比ECG和肌电位的频率成分更高的频率范围内,因此可以使用高通或带通滤波来专门隔离SKNA。neuECG是电压校准的,并且不需要侵入性手术来将电极刺入神经中,因此具有优于显微神经造影术的优点。在这里,我们提出了一个协议,
neuECG is the simultaneous noninvasive recording of ECG and skin sympathetic nerve activity and thus can directly record sympathetic nerve activity over a long period of time without the need for invasive procedures.neuECG, the simultaneous noninvasive recording of ECG and skin sympathetic nerve activity (SKNA), directly records sympathetic nerve activity over a long period of time. It can be used to measure sympathetic tone in healthy subjects and in subjects with non-cardiovascular diseases. The electrical activity that can be measured on the surface of the skin originates from the heart, the muscle or nerve structures. Because the frequency content of nerve activity falls in a higher frequency range than that of the ECG and myopotential, it is possible to use high-pass or band-pass filtering to specifically isolate the SKNA. neuECG is voltage calibrated and does not require invasive procedures to impale electrodes in nerves and thus has advantages over microneurography. Here, we present a protocol that takes