CT MUSCLE IMAGING AND THE CLINICAL-ASSESSMENT OF NEUROMUSCULAR DISEASE
CT MUSCLE IMAGING AND THE CLINICAL-ASSESSMENT OF NEUROMUSCULAR DISEASE
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DOI：
10.1002/mus.880180706
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发表时间：
1995-07-01
期刊：
影响因子：
3.4
通讯作者：
THAKKAR, C
中科院分区：
文献类型：
--
作者：
SWASH, M;BROWN, MM;THAKKAR, C
20例神经源性疾病、多发性肌炎或肌营养不良的患者采用标准方案进行临床评估，并通过肢体、肢带和躯干肌肉的CT成像进行评估。在这些患者的每一侧26个动作进行了MRC评分，并通过CT成像评估20块肌肉，临床和CT结果可以进行比较，在盲法评估中，每侧10块肌肉。对CT肌肉图像进行了定量评估。CT图像显示出惊人的异常，即使在许多肌肉的正常强度的临床测试，不对称的参与肌肉被发现在所有的疾病研究，即使没有怀疑在临床检查。肌营养不良患者肌肉的异常程度高于神经源性疾病患者，多发性肌炎患者肌肉的衰减值介于其他两组之间。衰减值非常低的“褪色”外观非常提示肌营养不良症，椎旁肌和腹直肌受累在神经性疾病中并不常见。股薄肌相对不易退变，CT成像可增强对神经肌肉疾病患者的临床评估，常能发现意想不到的异常。(C)1995年，John Wiley and Sons，Inc.
Twenty patients with neurogenic disorders, polymyositis, or muscular dystrophies were assessed clinically and by CT imaging of limb, limb girdle, and trunk muscles, using a standard protocol. On each side of these patients 26 movements were graded by the MRC scale, and 20 muscles were assessed by CT imaging, The clinical and CT findings could be compared, in a blind evaluation, in 10 muscles on each side. A quantitative assessment of the CT muscle images were also made. The CT images showed striking abnormalities, even in many muscles of normal strength by clinical testing, Asymmetrical involvement of muscles was found in all the disorders studied, even when not suspected on clinical examination. Muscles in patients with muscular dystrophy were more abnormal than those in patients with neurogenic disorders, In polymyositis the attenuation values were intermediate to the other two groups. A ''washed-out'' appearance with very low attenuation values was very suggestive of muscular dystrophy, Involvement of paraspinal and rectus abdominis muscles was uncommon in neurogenic disorders. The gracilis muscle was relatively resistant to degeneration, CT imaging can enhance the clinical assessment of patients with neuromuscular disease, often revealing unexpected abnormalities. (C) 1995 John Wiley and Sons, Inc.