THE ALIEN HAND AND RELATED SIGNS
THE ALIEN HAND AND RELATED SIGNS
复制标题
DOI：
10.1136/jnnp.55.9.806
复制
发表时间：
1992-09-01
影响因子：
11
通讯作者：
JANKOVIC, J
中科院分区：
文献类型：
--
作者：
DOODY, RS;JANKOVIC, J
肢体异位症状包括当视觉线索被移除时无法识别肢体的所有权，感觉身体的某个部位是外来的，受影响的身体部位的拟人化，以及被认为是不受自愿控制的自主活动。虽然手最常受影响，但任何肢体或肢体组合都可能符合异肢标准。异手手势应保留在手感觉陌生并可观察到的不自主运动活动的情况下。为了描述这一现象，本文描述了7名有异手势和其他运动或行为表现的患者。病因包括多发梗死和皮质基底神经节变性（CBD）。在本研究中，所有患者都有对口头命令的失用症和双手协调问题。大多数人表现出非目标导向的不自主运动行为，2人有自毁性运动行为。由于任何一种病因，异手会发生抓握反射。皮质反射性肌阵挛常见于CBD患者。本文回顾了异手症的现象学频谱，提出了一种诊断方案，并讨论了异手症可能的解剖学基础。
Alien limb sign includes failure to recognise ownership of one's limb when visual cues are removed, a feeling that one body part is foreign, personification of the affected body part, and autonomous activity which is perceived as outside voluntary control. Although the hand is most frequently affected, any limb or combination of limbs may fulfil the alien limb criteria. Alien hand sign should be reserved for cases in which the hand feels foreign together with observable involuntary motor activity. To characterise this phenomenon, seven patients with alien hand sign and other motor or behavioural manifestations are described. Aetiologies included multiple infarcts and cortobasal ganglionic degeneration (CBD). In this study, all patients had apraxia in response to verbal commands and problems with bimanual coordination. Most displayed non-goal directed involuntary motor activities, and two had self destructive motor behaviours. Grasp reflex occurred with alien hand due to either aetiology. Cortical reflex myoclonus was frequently seen in CBD patients. The phenomenological spectrum is reviewed, a diagnostic protocol proposed, and possible anatomical bases of alien hand discussed.