HermesC: Low-Power Wireless Neural Recording System for Freely Moving Primates
HermesC: Low-Power Wireless Neural Recording System for Freely Moving Primates
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DOI：
10.1109/tnsre.2009.2023293
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发表时间：
2009-08-01
影响因子：
4.9
通讯作者：
Shenoy, Krishna V.
中科院分区：
文献类型：
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作者：
Chestek, Cynthia A.;Gilja, Vikash;Shenoy, Krishna V.
神经假体系统有可能恢复截肢者或患有神经损伤或疾病的患者失去的功能。目前的系统主要是为不动的患者设计的，例如在相当静态的、仔细定制的环境中工作的四肢瘫痪者。然而，一个活跃的病人，如截肢者，在正常的动态，日常环境中，在运动的神经控制方面可能是完全不同的。为了在更不受约束的自然环境中研究运动控制，我们试图开发一种自由移动的人类动物模型。因此，我们开发并测试了HermesC-INI 3，这是一种用于记录和无线传输植入自由活动的恒河猴电极阵列的神经数据的系统。该系统基于集成神经接口（INI 3）微芯片，该微芯片通过类似于900 MHz的无线信道放大，数字化和传输神经数据。无线传输在自由空间中具有类似于4 m的范围。该器件的总功耗为15.8 mA和63.2 mW。在单个2 A-hr电池组上，该设备连续运行约6天。定制IC的尺寸和功耗更小，可以实现比以前的灵长类系统更小的封装（51 x 38 x 38 mm（3））。HermesC-INI 3系统用于记录和遥测在15.7 kSps下来自在饲养笼中进行常规日常活动的猴子的宽带神经数据的一个通道。
Neural prosthetic systems have the potential to restore lost functionality to amputees or patients suffering from neurological injury or disease. Current systems have primarily been designed for immobile patients, such as tetraplegics functioning in a rather static, carefully tailored environment. However, an active patient such as amputee in a normal dynamic, everyday environment may be quite different in terms of the neural control of movement. In order to study motor control in a more unconstrained natural setting, we seek to develop an animal model of freely moving humans. Therefore, we have developed and tested HermesC-INI3, a system for recording and wirelessly transmitting neural data from electrode arrays implanted in rhesus macaques who are freely moving. This system is based on the integrated neural interface (INI3) microchip which amplifies, digitizes, and transmits neural data across a similar to 900 MHz wireless channel. The wireless transmission has a range of similar to 4 m in free space. All together this device consumes 15.8 mA and 63.2 mW. On a single 2 A-hr battery pack, this device runs contiguously for approximately six days. The smaller size and power consumption of the custom IC allows for a smaller package (51 x 38 x 38 mm(3)) than previous primate systems. The HermesC-INI3 system was used to record and telemeter one channel of broadband neural data at 15.7 kSps from a monkey performing routine daily activities in the home cage.