Quadriceps muscle strength, radiographic knee osteoarthritis and knee pain: the ROAD study.
Quadriceps muscle strength, radiographic knee osteoarthritis and knee pain: the ROAD study.
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DOI：
10.1186/s12891-015-0737-5
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发表时间：
2015-10-16
影响因子：
2.3
通讯作者：
Yoshimura N
中科院分区：
文献类型：
--
作者：
Muraki S;Akune T;Teraguchi M;Kagotani R;Asai Y;Yoshida M;Tokimura F;Tanaka S;Oka H;Kawaguchi H;Nakamura K;Yoshimura N
这项研究的目的是通过骨关节炎/骨质疏松抗残疾研究(ROAD)的大规模人群队列研究，阐明股四头肌肌力与膝关节疼痛的关系。在第3次ROAD研究的2 566名受试者中，本研究分析了2 152名完成X光检查和肌肉力量和质量测量的受试者(男性6 90名，女性1 462名；平均年龄71.6 ± 12.2岁)。膝关节疼痛由经验丰富的骨科医生评估。膝关节骨关节炎(OA)按Kellgren-Lawrence(KL)分级。股四头肌训练机(日本东京Alcare株式会社QTM-05F)和MC-190身体成分分析仪(Tanita公司，日本东京)分别测量股四头肌肌力和腿部肌肉质量。调整年龄和体重指数后，股四头肌肌力和负重指数(WBI：股四头肌重量)与膝关节疼痛显著相关，而握力和下肢肌肉质量与膝关节疼痛无关。股四头肌肌力与膝关节疼痛的显著相关性与放射学膝关节骨性关节炎无关。目前的横断面研究表明，股四头肌肌力与膝关节疼痛之间存在独立关联。本文的在线版本(doi：10.1186/s12891-0150737-5)包含补充材料，授权用户可以使用。
The objective of this study was to clarify the association of quadriceps muscle strength with knee pain using a large-scale, population-based cohort of the Research on Osteoarthritis/osteoporosis Against Disability (ROAD) study. From the 2566 subjects at the third visit of the ROAD study, the present study analyzed 2152 subjects who completed radiographic examinations and measurements of muscle strength and mass (690 men and 1462 women; mean age, 71.6 ± 12.2 years). Knee pain was assessed by an experienced orthopedist. Knee osteoarthritis (OA) was defined according to Kellgren-Lawrence (KL) grade. Quadriceps muscle strength and muscle mass at the lower limbs were measured by the Quadriceps Training Machine (QTM-05F, Alcare Co., Ltd. Tokyo, Japan) and the Body Composition Analyzer MC-190 (Tanita Corp., Tokyo, Japan), respectively. Quadriceps muscle strength and weight bearing index (WBI: quadriceps muscle strength by weight) were significantly associated with knee pain after adjustment for age and body mass index, whereas grip strength and muscle mass at the lower limbs were not. The significant association of quadriceps muscle strength with knee pain was independent of radiographic knee OA. The present cross-sectional study showed an independent association of quadriceps muscle strength with knee pain. The online version of this article (doi:10.1186/s12891-015-0737-5) contains supplementary material, which is available to authorized users.