Effect of nerve block on response of forearm blood flow to local temperature.
Effect of nerve block on response of forearm blood flow to local temperature.
复制标题
神经阻滞对前臂血流对局部温度反应的影响。
DOI：
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发表时间：
1986
影响因子：
3.3
通讯作者：
M. Durkin
中科院分区：
文献类型：
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作者：
C. Wenger;L. A. Stephenson;M. Durkin
为了确定神经递质在前臂血流量(ABF)对局部(前臂)皮肤温度(TSK)反应中的作用，我们测量了6名受试者在臂丛神经阻滞前(对照组)和臂丛神经阻滞(BPB)后25~40℃皮肤温度(TSK)时的ABF。对照实验是在27-29摄氏度的环境温度下进行的，调整后的环境温度将受试者的整体热感降至最低。TSK是通过将一股可控温度的气流吹过包裹手臂的塑料袋来调节的。我们首先将tk降低到25摄氏度，20分钟后开始用惠特尼应变计测量ABF。然后我们将TSK升高2.5摄氏度至40摄氏度，并在每个TSK水平上每30 S测量一次ABF，持续至少10分钟。对照组平均ABF从25℃时的1.1mlX100ml-1×min-1升至32.5℃时的2.1mlX100ml-1Xmin-1，升至40℃时的13.7mlX100ml-1Xmin-1；TSK对ABF的影响非常显著(P<0.0001.0 1)，而BPB的作用不显著(P约等于0.2)。在体温正常时，TSK对ABF的影响在很大程度上不受神经活动的影响，因为这种作用不受神经阻滞的影响。
To determine the role of neurotransmitter in the response of forearm blood flow (ABF) to local (forearm) skin temperature (Tsk) we measured ABF of six subjects at Tsk from 25 to 40 degrees C before (control) and after brachial plexus block (BPB). Control experiments were conducted in an ambient temperature of 27-29 degrees C, adjusted to minimize the subject's overall thermal sensation. Tsk was regulated by blowing a controlled-temperature airstream through a plastic bag enclosing the arm. We first lowered Tsk to 25 degrees C and after 20 min began to measure ABF with Whitney strain gauges. We then raised Tsk by 2.5 degrees C steps to 40 degrees C and measured ABF every 30 s for at least 10 min at each level of Tsk. Mean ABF rose from 1.1 ml X 100 ml-1 X min-1 at Tsk of 25 degrees C to 2.1 ml X 100 ml-1 X min-1 at 32.5 degrees C to 13.7 ml X 100 ml-1 X min-1 at 40 degrees C in control experiments and from 2.8 to 4.4 to 14.8 ml X 100 ml-1 X min-1 after BPB. The effect of Tsk on ABF was highly significant (P less than 0.0001) but the effect of BPB was not (P approximately equal to 0.2). At thermoneutrality, the effect of Tsk on ABF is largely independent of neural activity, since this effect is unaffected by nerve block.