The time course of neural changes underlying auditory perceptual learning
The time course of neural changes underlying auditory perceptual learning
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DOI：
10.1101/lm.46502
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发表时间：
2002-05-01
影响因子：
2
通讯作者：
Dominguez-Marin, E
中科院分区：
文献类型：
--
作者：
Atienza, M;Cantero, JL;Dominguez-Marin, E
感知的改善发生在培训课程中以及从一个课程到下一个课程的过程中。本研究旨在通过反映前注意过程的听觉事件相关电位（ERP）的变化来确定知觉学习的调整过程。受试者接受训练，能够在一次训练中辨别两种复杂的听觉模式。在训练前后记录 ERP，而受试者则阅读书籍并忽略刺激。就在受试者学会有意识地区分这两种模式之后，ERP 引发了一种称为失配负性 (MMN) 的负波，它表示对同质听觉序列变化的自动检测。 12、24、36 和 48 小时后，即测试辨别任务表现之前，再次记录 ERP。跟踪会话数小时后发现了额外的行为和神经生理学变化：24 小时 P2 增强，随后反应时间缩短，36 小时 MMN 增强。这些结果表明，区分两种复杂听觉模式的表现的提高伴随着不同时间范围内演变的不同的学习依赖性神经生理学事件，支持了快速和缓慢的神经变化是获得改善的感知的基础的假设。
Improvement in perception takes place within the training session and from one session to the next. The present study aims at determining the tune course of perceptual learning as revealed by changes in auditory event-related potentials (ERPs) reflecting preattentive processes. Subjects were trained to discriminate two complex auditory patterns in a single session. ERPs were recorded just before and after training, while subjects read a book and ignored stimulation. ERPs shoved a negative wave called mismatch negativity (MMN)-which indexes automatic detection of a change in a homogeneous auditory sequence-just after subjects learned to consciously discriminate the two patterns. ERPs were recorded again 12, 24, 36, and 48 h later, just before testing performance on the discrimination task. Additional behavioral and neurophysiological changes were found several hours after the trailing session: an enhanced P2 at 24 h followed by shorter reaction times, and an enhanced MMN at 36 h. These results indicate that gains in performance on the discrimination of two complex auditory patterns are accompanied by different learning-dependent neurophysiological events evolving within different time frames, supporting the hypothesis that fast and slow neural changes underlie the acquisition of improved perception.