Baseline and previous physical activity in relation to mortality in elderly men - The Zutphen Elderly Study
Baseline and previous physical activity in relation to mortality in elderly men - The Zutphen Elderly Study
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DOI：
10.1093/oxfordjournals.aje.a009960
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发表时间：
1999-12-15
影响因子：
5
通讯作者：
Kromhout, D
中科院分区：
文献类型：
--
作者：
Bijnen, FCH;Feskens, EJM;Kromhout, D
了解身体活动变化对死亡风险的影响可能有助于研究人员阐明干预策略。本研究调查了472名荷兰老年男性在基线和5年前的体力活动与全因死亡风险的关系。估计了1990-1995年死亡率与1990年和1985年体力活动水平之间关系的相对风险。对基线年龄、慢性疾病、功能状态和生活方式因素进行了调整。与之前的体力活动水平（调整后的p趋势= 0.39）相比，基线体力活动总时间与死亡风险呈负相关（p趋势= 0.004;对于最活跃的三分位数与最不活跃的三分位数，相对风险= 0.44; 95%置信区间：0.25，0.80）。在将总体力活动分为不同强度的活动或四种不同类型的活动后，没有观察到一致的关联。相对于保持身体活跃的生活方式（即，步行或骑自行车20分钟，每周至少三次），在两个调查年中，观察到从采取积极的生活方式到成为久坐者和保持久坐者的风险增加梯度（p趋势= 0.004）。最近的体力活动水平比5年前的活动对老年男性的死亡风险更重要。与保持体力活动相比，久坐或保持久坐与死亡风险增加显著相关。
Understanding the effect of changes in physical activity on mortality risk may help researchers clarify intervention strategies. This study investigated associations of physical activity at baseline and 5 years previously with all-cause mortality risk in a cohort of 472 elderly Dutch men. Relative risks were estimated for relations between mortality in 1990-1995 and physical activity levels in 1990 and 1985. Adjustments were made for baseline age, chronic diseases, functional: status, and lifestyle factors. In contrast to previous levels of physical activity (adjusted p-trend = 0.39), baseline total time spent in physical activity was inversely associated with mortality risk (p-trend = 0.004; for the most active tertile vs. the least active, relative risk = 0.44; 95% confidence interval: 0.25, 0.80). No consistent associations were observed after fractionating total physical activity into activities of differing intensity or into four different types of activity. Relative to maintaining a physically active lifestyle (i.e., walking or bicycling for 20 minutes at least three times per week) in both survey years, a gradient of increasing risk was observed from adopting an active lifestyle to becoming sedentary td remaining sedentary (p-trend = 0.004). Recent levels of physical activity were more important for mortality risk among elderly men than activity 5 years previously Becoming or remaining sedentary was significantly associated with increased mortality risk in comparison with remaining physically active.