Different foveal schisis patterns in each retinal layer in eyes with hereditary juvenile retinoschisis evaluated by en-face optical coherence tomography.
Different foveal schisis patterns in each retinal layer in eyes with hereditary juvenile retinoschisis evaluated by en-face optical coherence tomography.
复制标题
通过正面光学相干断层扫描评估患有遗传性青少年视网膜劈裂的眼睛每个视网膜层的不同中心凹劈裂模式。
DOI：
10.1007/s00417-016-3552-2
复制
发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Azuma N.
中科院分区：
文献类型：
--
作者：
Yoshida-Uemura T;Katagiri S;Yokoi T;Nishina S;Azuma N.
目的应用光学相干断层扫描（OCT）对遗传性青少年视网膜裂的眼裂结构进行分析。方法回顾性分析9例男孩（平均年龄±标准差10.6±4.0岁）16只眼的ct图像。中央凹OCT水平影像显示1眼内核层（INL）分裂（6.3%），12眼神经节细胞层（GCL）和内层分裂（75.0%），2眼内核层和外丛状层（OPL）分裂（12.5%），1眼GCL、内层和外丛状层分裂（6.3%）。正面OCT图像显示视网膜各层具有特征性的分裂模式，其表现为下皮层中央凹区有多个低反射孔，中央凹区有辐条状孔，下皮层中央凹区有网状孔，下皮层有多个低反射多边形腔，并有分区。结论采用正面OCT成像的结果明确了GCL、INL和OPL的不同分裂形成模式，从而进一步认识了遗传性青少年视网膜分裂的结构。
PurposeTo analyze the structures of schisis in eyes with hereditary juvenile retinoschisis using en-face optical coherence tomography (OCT) imaging.MethodsIn this retrospective observational study, we reviewed the medical records of patients with hereditary juvenile retinoschisis who underwent comprehensive ophthalmic examinations including swept-source OCT.ResultsOCT images were obtained from 16 eyes of nine boys (mean age ± standard deviation, 10.6 ± 4.0 years). The horizontal OCT images at the fovea showed inner nuclear layer (INL) schisis in one eye (6.3 %), ganglion cell layer (GCL) and INL schisis in 12 eyes (75.0 %), INL and outer plexiform layer (OPL) schisis in two eyes (12.5 %), and GCL, INL, and OPL schisis in one eye (6.3 %). En-face OCT images showed characteristic schisis patterns in each retinal layer, which were represented by multiple hyporeflective holes in the parafoveal region in the GCL, a spoke-like pattern in the foveal region, a reticular pattern in the parafoveal region in the INL, and multiple hyporeflective polygonal cavities with partitions in the OPL.ConclusionsOur results using en-face OCT imaging clarified different patterns of schisis formation among the GCL, INL, and OPL, which lead to further recognition of structure in hereditary juvenile retinoschisis.