Waste-Free Swift Synthesis of Symmetrical and Unsymmetrical Diarylmethyl Thioethers from Diaryl Carbinols
Waste-Free Swift Synthesis of Symmetrical and Unsymmetrical Diarylmethyl Thioethers from Diaryl Carbinols
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DOI：
10.1055/s-0036-1589022
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发表时间：
2017-08-01
影响因子：
2.6
通讯作者：
Peddinti, Rama Krishna
中科院分区：
文献类型：
--
作者：
Singh, Pallavi;Peddinti, Rama Krishna
报道了一种以二芳基甲醇和硫醇为原料合成对称和不对称二芳基甲基硫醚的无废快速工艺。硫醇范围包括具有供电子和吸电子基团的烷基和芳基硫醇。反应时间短、原子经济性高、活化剂价格低廉、不含后处理和芳基卤化物、可实现克级合成是新工艺的显著特点。
A waste-free and swift protocol to synthesize symmetrical and unsymmetrical diarylmethyl thioethers from diaryl carbinols and thiols in good to quantitative yields is reported. The thiol scope included alkyl and aryl thiols bearing electron-donating and electron-withdrawing groups. Short reaction time, high atom economy, inexpensive activator, free from workup and aryl halides, and gram-scale synthesis are the significant features of the new protocol.