The relationship between severity and extent of spinal involvement and spinal mobility and physical functioning in patients with ankylosing spondylitis
The relationship between severity and extent of spinal involvement and spinal mobility and physical functioning in patients with ankylosing spondylitis
复制标题
DOI：
10.1007/s10067-005-0180-3
复制
发表时间：
2006-11-01
影响因子：
3.4
通讯作者：
Gunaydin, Rezzan
中科院分区：
文献类型：
--
作者：
Kaya, Taciser;Gelal, Fazil;Gunaydin, Rezzan
本研究旨在确定强直性脊柱炎 (AS) 的脊柱放射学变化、脊柱活动度和身体功能之间的关系。本研究纳入了根据修订后的纽约 AS 标准诊断为 AS 的 31 名患者。使用三种放射照相评分方法来评估脊柱损伤。通过使用斯托克强直性脊柱炎脊柱评分（SASSS）和巴斯强直性脊柱炎放射照相指数-脊柱（BASRI-S）评估脊柱受累的严重程度。为了评估脊柱受累的程度，根据 Braun 等人定义的 AS 分级系统计算放射学结果显示可归因于 AS 的椎骨总数 [受累椎骨数量 (NoVI)]。使用Windows Statistical Package for the Social Sciences 13.0 进行统计分析，包括双变量相关、Spearman 相关和多元线性回归分析。 NoVI 与改良 Schober 和脊柱侧屈呈负相关，与枕骨到墙的距离和 BASMI 呈正相关。 SASSS 与修正的 Schober 呈负相关。 BASRI-S与修正Schober呈负相关，与BASMI呈正相关。当以 BASMI 和巴斯强直性脊柱炎功能指数为因变量时，仅发现 NoVI 与 BASMI 相关。在我们的数据中，与其他放射学评分（SASSS 和 BASRI-S）相比，脊柱受累程度 (NoVI) 显示与改良 Schober 和 BASMI 等脊柱测量值具有更显着的相关性。此外，由于仅发现 NoVI 与 BASMI 相关，因此我们可以得出结论，脊柱受累程度（也包括胸椎）会影响脊柱测量。
The present study was undertaken to determine the relationship between spinal radiological changes of ankylosing spondylitis (AS), spinal mobility, and physical functioning. Thirty-one patients diagnosed as AS according to the modified New York criteria for AS were included in this study. Three radiographic scoring methods were used to assess spinal damage. Severity of spinal involvement was assessed by using Stoke Ankylosing Spondylitis Spine Score (SASSS) and Bath Ankylosing Spondylitis Radiographic Index-Spine (BASRI-S). To assess the extent of spinal involvement, the total number of vertebrae showing radiological findings attributable to AS [number of vertebrae involved (NoVI)] was calculated according to the AS grading system defined by Braun et al. Statistical analysis, consisting of bivariate correlation, Spearman correlation, and multiple linear regression analysis, was performed using Windows Statistical Package for the Social Sciences 13.0. NoVI was negatively correlated with modified Schober and lateral spinal flexion and was positively correlated with occiput-to-wall distance and BASMI. SASSS was negatively correlated with the modified Schober. BASRI-S was negatively correlated with the modified Schober and positively correlated with BASMI. When BASMI and Bath Ankylosing Spondylitis Functional Index were taken as dependent variables, only the NoVI was found to be associated with BASMI. In our data, the extent of spinal involvement (NoVI) showed a more significant correlation with spinal measurements such as modified Schober and BASMI as compared with the other radiologic scores (SASSS and BASRI-S). Furthermore, because only the NoVI was found to be associated with BASMI, we can conclude that the extent of spinal involvement, which also includes thoracic vertebrae, affects spinal measurements.