The diagnostic validity of anxiety disorders and their relationship to depressive illness.
The diagnostic validity of anxiety disorders and their relationship to depressive illness.
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焦虑症的诊断有效性及其与抑郁症的关系。
DOI：
10.1176/ajp.142.7.787
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Heninger,GR
中科院分区：
文献类型：
--
作者：
Breier,A;Charney,DS;Heninger,GR
关于焦虑症的诊断分类存在几个严重的问题。作者检查了广泛性焦虑症和惊恐障碍的诊断有效性，并探讨了它们与重性抑郁症的关系，批判性地回顾了相关的描述性、终生发生率、家庭和遗传、药物治疗和神经生物学研究。惊恐障碍的诊断有效性得到了有力的支持，但很少有数据支持广泛性焦虑障碍的单独诊断分类。此外，一些证据表明，某些形式的恐慌症和重度抑郁症可能存在共同的脆弱性。这些研究结果的诊断应用，治疗和未来的研究进行了讨论。
Several serious questions exist regarding the diagnostic classification of anxiety disorders. The authors examine the diagnostic validity of generalized anxiety disorder and panic disorder and explore their relationship to major depression, critically reviewing relevant descriptive, lifetime occurrence, family and genetic, drug treatment, and neurobiological studies. There is strong support for the diagnostic validity of panic disorder, but few data are found to support a separate diagnostic classification of generalized anxiety disorder. In addition, several lines of evidence suggest that a common vulnerability may exist for some forms of panic disorder and major depression. The implications of these findings for diagnostic application, treatment, and future research are discussed.