Isolation of Yersinia-specific T cell clones from the synovial membrane and synovial fluid of a patient with reactive arthritis.
Isolation of Yersinia-specific T cell clones from the synovial membrane and synovial fluid of a patient with reactive arthritis.
复制标题
从反应性关节炎患者的滑膜和滑液中分离耶尔森氏菌特异性 T 细胞克隆。
作者：
N. Viner;L. Bailey;P. Life;Paul A. Bacon;J. Gaston
Synovial fluid (SF) mononuclear cells from patients with reactive arthritis (ReA) proliferate in vitro when challenged with ReA-associated bacteria, the maximal response being for the organism causing the triggering infection. We report the results of a study of the antigenic specificity of synovial T lymphocytes from an HLA-B27 positive ReA patient whose SF mononuclear cells responded preferentially to Yersinia antigens. This is the first report of the isolation of Yersinia-specific T cell clones from synovial membrane (obtained by closed-needle synovial biopsy). We present a detailed analysis of these clones, together with others obtained from the SF.
影响因子：
27.4
作者：
LAHESMAARANTALA, R;GRANFORS, K;TOIVANEN, A
通讯作者：
TOIVANEN, A
耶尔森氏菌中的 IgA 抗耶尔森氏菌抗体引发反应性关节炎。
影响因子：
27.4
作者：
Granfors,K;Toivanen,A
通讯作者：
Toivanen,A