Sinonasal intestinal- and non-intestinal-type adenocarcinoma in China: a retrospective study of 14 cases

Sinonasal intestinal- and non-intestinal-type adenocarcinoma in China: a retrospective study of 14 cases
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中国鼻腔肠型和非肠型腺癌14例回顾性研究

DOI:
10.1080/00016489.2023.2175032
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发表时间:
2023
影响因子:
1.4
通讯作者:
Hongmeng Yu
Hongmeng Yu
中科院分区:
医学4区
文献类型:
--
作者:
Guangyao Li;Yuxuan Shi;Quan Liu;Huankang Zhang;K. Xue;Xiaole Song;Ye Gu;Xicai Sun;Q. Dai;Hongmeng Yu

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摘要背景在中国,关于鼻腔和鼻窦腺癌的流行病学报道有限。目的本研究旨在描述中国单一机构治疗这些恶性肿瘤的经验。材料与方法我们对2019年1月至2021年12月期间收治的鼻腔和鼻窦腺癌患者进行了回顾性图表分析。肿瘤分期基于美国癌症联合委员会第8版,用于鼻窦恶性肿瘤。结果本组病例包括10名男性和4名女性(平均年龄,54.5 [范围,14-80]岁)。鼻出血和鼻塞是最常见的临床表现10例(71.4%)。10例(71.4%)在诊断时为T4期疾病,但没有患者有淋巴结或远处转移。后上隔(100.0%)和中鼻甲(92.8%)是最易受肿瘤侵袭的两个部位。所有患者均接受内镜切除术作为初始治疗; 1例患者死亡。结论和意义在中国,这些恶性肿瘤与接触某些物质有关,但诊断可能会延迟。内窥镜切除术是鼻腔和鼻窦腺癌的一种合适的治疗选择。
Abstract Background In China, reports on the epidemiology of adenocarcinomas of the nasal cavity and paranasal sinuses are limited. Aim This study aimed to describe the experience of a single institution in China in treating these malignant tumours. Materials and Methods We conducted a retrospective chart review of patients with adenocarcinoma of the nasal cavity and paranasal sinuses admitted between January 2019 and December 2021. Tumour staging was based on the American Joint Committee on Cancer, 8th edition, for sinonasal malignancies. Results The series included 10 men and 4 women (mean age, 54.5 [range, 14–80] years). Epistaxis and nasal obstruction were the most common clinical manifestations in 10 (71.4%) patients. Ten (71.4%) had stage T4 disease at diagnosis, but no patient had lymph node or distant metastasis. The posterosuperior septum (100.0%) and middle turbinate (92.8%) were the two sites most vulnerable to tumour invasion. All patients underwent endoscopic resection as the initial treatment; one patient died. Conclusions and Significance In China, these malignancies are related to exposure to certain substances; however, diagnosis can be delayed. Endoscopic resection is a suitable treatment option for adenocarcinomas of the nasal cavity and paranasal sinuses.
DOI: --
发表时间: 2016
期刊:
影响因子: --
作者:
Sakata K;Ono T;Koga N;Takeshige N;Rikimaru H;Umeno H;Kiyokawa K;Morioka M
通讯作者: Morioka M