Affect processing and positive syndrome schizotypy in cannabis users.
Affect processing and positive syndrome schizotypy in cannabis users.
复制标题
影响大麻使用者的加工和阳性综合症分裂型。
DOI：
10.1016/j.psychres.2007.02.010
复制
发表时间：
2008
影响因子：
11.3
通讯作者：
Gardner,WendiL
中科院分区：
文献类型：
--
作者：
Skosnik,PatrickD;Park,Sohee;Dobbs,Laura;Gardner,WendiL
While cannabis is associated with positive syndrome schizophrenia (SZ), it is unclear whether cannabinoids are also related to negative symptoms such as affective blunting. We examined whether cannabis use is associated with schizotypy and utilized event-related potentials (ERPs) to assess affect processing. Cannabis users demonstrated increased P300 amplitudes for unpleasant trait words, and demonstrated higher positive syndrome schizotypy which correlated with levels of cannabis use. The cannabis group also exhibited lower negative syndrome schizotypy. The lack of blunted responses during the affect ERP and decreased negative subscale schizotypy scores provide evidence that the endocannabinoid theory of schizophrenia may be primarily relevant in relation to positive syndrome SZ.
