Intelligence in childhood and chronic widespread pain in middle age: The National Child Development Survey
Intelligence in childhood and chronic widespread pain in middle age: The National Child Development Survey
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DOI：
10.1016/j.pain.2012.07.027
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发表时间：
2012-12-01
期刊：
影响因子：
7.4
通讯作者：
Batty, G. David
中科院分区：
文献类型：
--
作者：
Gale, Catharine R.;Deary, Ian J.;Batty, G. David
心理因素被认为在慢性广泛性疼痛的病因学中起一定作用。我们调查了来自全国儿童发展调查（1958年英国出生队列）的6902名男性和女性儿童期智力与成年期慢性广泛性疼痛风险之间的关系。参与者在11岁时进行了一般认知能力测试;根据美国流变学学会标准定义的慢性广泛性疼痛在45岁时进行了评估。使用对数二项回归估计风险比（RR）和95%置信区间（CI），调整性别和潜在混杂或中介因素。根据美国流变学学会的标准，慢性广泛性疼痛的风险随着智力的下降而逐步上升（P为线性趋势
Psychological factors are thought to play a part in the aetiology of chronic widespread pain. We investigated the relationship between intelligence in childhood and risk of chronic widespread pain in adulthood in 6902 men and women from the National Child Development Survey (1958 British Birth Cohort). Participants took a test of general cognitive ability at age 11 years; and chronic widespread pain, defined according to the American College of Rheumatology criteria, was assessed at age 45 years. Risk ratios (RRs) and 95% confidence intervals (CIs) were estimated using log-binomial regression, adjusting for sex and potential confounding or mediating factors. Risk of chronic widespread pain, defined according to the American College of Rheumatology criteria, rose in a stepwise fashion as intelligence fell (P for linear trend