Isolation and identification of a bacteriophage capable of infecting Streptococcus suis type 2 strains
Isolation and identification of a bacteriophage capable of infecting Streptococcus suis type 2 strains
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DOI：
10.1016/j.vetmic.2008.05.013
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发表时间：
2008-12-10
影响因子：
3.3
通讯作者：
Lu, C. P.
中科院分区：
文献类型：
--
作者：
Ma, Y. L.;Lu, C. P.
猪链球菌(S.suis)2型感染被认为是全球养猪业的主要问题。研究革兰氏阳性菌的生态和进化。然而。猪链球菌2型噬菌体对于理解目前的情况至关重要，人们对它们知之甚少。从健康巴马小型猪鼻拭子中分离到一株猪链球菌2型噬菌体，命名为SMP，并从微生物学和分子水平进行了鉴定。噬菌体SMP的头部长度为50 nm，尾长约为135 nm，基因组为线形双链DNA。噬菌体SMP的寄主范围仅限于24株猪链球菌2型菌株中的2株。噬菌体SMP基因组全长36,216个核苷酸，平均G+C含量为41.6%。(C)2008爱思唯尔B.V.保留所有权利。
Streptococcus suis (S. suis) type 2 infection is considered to be a major problem worldwide in the swine industry. Studying the ecology and evolution of the Gram-positive bacteria. However. at phages of S. suis type 2 would be crucial for understanding the present, very little is known about them. An S. suis type 2 bacteriophage, named SMP was isolated from nasal swabs of healthy Bama minipigs and was characterized at the microbiological and molecular levels. Phage SMP had an isometric head of 50 nm, a noncontractile tail of approximately 135 nm, and a linear double-stranded DNA genome. The host range of phage SMP was limited to 2 of 24 S. suis type 2 strains tested. The genome of phage SMP contained 36,216 bp with an average G + C content of 41.6%. (C) 2008 Elsevier B.V. All rights reserved.