Detection and identification of non-Candida albicans species in human oral lichen planus
Detection and identification of non-Candida albicans species in human oral lichen planus
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DOI：
10.1111/j.1348-0421.2010.00285.x
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发表时间：
2011-01-01
影响因子：
2.6
通讯作者：
Takahashi, Nobuhiro
中科院分区：
文献类型：
--
作者：
Masaki, Mika;Sato, Takuichi;Takahashi, Nobuhiro
在口腔扁平苔藓（OLP）患者的颊黏膜、舌背表面和龈上菌斑中检测和鉴定了念珠菌种类。将样品中的念珠菌在选择琼脂上培养，通过18S、5.8S和25/28S rRNA序列分析进行鉴定。假丝酵母在OLP患者中的分离率高于正常口腔黏膜患者。非。白色念珠菌仅从OLP患者中分离出来。这些结果支持了OLP受试者更有可能口腔定植念珠菌的观点，而非c。白色念珠菌在这种情况下特别存在。
Candida species were detected and identified in samples from the buccal mucosa, dorsal surface of the tongue and supragingival plaque of subjects with oral lichen planus (OLP). The Candida in the samples were cultured on selection agars, and identified by sequence analyses of 18S, 5.8S and 25/28S rRNA. The isolation frequency of Candida was higher in subjects with OLP than in those with healthy oral mucosa. Non-C. albicans were only isolated from people with OLP. These results support the notion that subjects with OLP are more likely to have oral colonization with Candida, and that non-C. albicans are specifically present in subjects with this condition.