Pleiotropic effect, clock genes, and reproductive isolation
Pleiotropic effect, clock genes, and reproductive isolation
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多效性效应、时钟基因和生殖隔离
DOI：
10.1007/s101440200023
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发表时间：
2002
影响因子：
1.7
通讯作者：
Takahisa Miyatake
中科院分区：
文献类型：
--
作者：
Takahisa Miyatake
摘要以瓜实蝇Bactrocera cucurbitae（Coquillett）为模式种，解释了生物钟基因多效性控制生活史和行为特征导致生殖隔离的机制。 瓜蝇每天交配一次，在黄昏。选择的生活史性状的人口表现出相关的反应，在白天的交配时间。例如，选择较快（较慢）发育的果蝇种群交配时间较早（较晚）。昼夜节律控制着交配的时间。在恒定的黑暗中的昼夜节律周期约为22小时，选择了一个短的发展时期和约31小时，选择了一个长的发展时期的线。所选品系间的杂交数据表明，发育期受多基因控制，而昼夜节律期可能受单个时钟基因控制。这些结果表明，一个时钟基因多效性控制发育和昼夜节律的时期，在瓜蝇。生殖隔离往往是适应不同环境或生境的间接（多效性）结果。例如，时间或季节性偏移的生态位可以选择具有不同发育特征的生物。这些发育差异可能会无意中导致生殖隔离的各种手段，包括交配活动模式的变化。选择发育期的人口之间的交配时间的差异转化为显着的前合子隔离，作为衡量择偶测试。若种群间交配时间相差大于1h，则隔离指数显著大于零。这些发现表明，交配前隔离可以建立一个时钟基因的多效性效应。有许多例子表明，繁殖时间的差异阻止了种群之间的基因流动，例如海洋生物的产卵时间，被子植物的开花时间以及昆虫的交配时间。在这样的生物中，如果昼夜节律和生殖性状之间存在遗传相关性，那么对生活史性状的多样性趋异选择往往会通过时钟基因加速生殖隔离的进化。自然种群可能通过漂移、直接自然选择或遗传相关的副产品效应而在生殖时间上产生分歧。无论如何，时钟基因是生殖隔离的关键。
Abstract The mechanism by which a clock gene pleiotropically controlling life history and behavioral traits causes reproductive isolation is explained using a model species, the melon fly, Bactrocera cucurbitae (Coquillett) (Diptera: Tephritidae). Melon flies mate once a day, at dusk. The population selected for life history traits exhibits correlated responses in the time of mating during the day. For example, the fly populations selected for faster (slower) development have an earlier (later) time of mating. A circadian rhythm controls the time of mating. The circadian periods in constant darkness were about 22 h in lines selected for a short developmental period and about 31 h in lines selected for a long developmental period. The data on crosses between the selected lines indicated that the developmental period is controlled by a polygene, whereas the circadian period may be controlled by a single clock gene. These results suggest a clock gene pleiotropically controls developmental and circadian periods in the melon fly. Reproductive isolation may often evolve as an indirect (pleiotropic) consequence of adaptation to different environments or habitats. For example, niches that are temporally or seasonally offset can select organisms with different developmental characteristics. These developmental differences can inadvertently cause reproductive isolation by a variety of means including shifts in mating activity patterns. The difference in time of mating between populations selected for developmental period translated into significant prezygotic isolation, as measured by mate choice tests. If the mating time between populations differed more than 1 h, the isolation index was significantly higher than zero. These findings indicate that premating isolation can be established by a pleiotropic effect of a clock gene. There are many examples in which the difference in timing of reproduction prevents gene flow between populations, such as the egg spawning time in marine organisms, the flowering time in angiosperms, and the time of mating in insects. In such organisms, if genetic correlations between circadian rhythm and reproductive traits exist, multifarious divergent selection for life history traits would often accelerate the evolution of reproductive isolation through clock genes. Natural populations may diverge in reproduction time through drift, direct natural selection for time of reproduction, or as a by-product effect of genetic correlations. In any case, clock genes are keys in reproductive isolation.
影响因子：
56.9
作者：
Glossop, NRJ;Lyons, LC;Hardin, PE
通讯作者：
Hardin, PE
生物钟的遗传分析。
影响因子：
18.2
作者：
Dunlap,JC
通讯作者：
Dunlap,JC
DOI：
10.1073/pnas.77.11.6729
发表时间：
1980-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
KYRIACOU, CP;HALL, JC
通讯作者：
HALL, JC