Use of dipsticks for rapid diagnosis of cholera caused by Vibrio cholerae O1 and O139 from rectal swabs
Use of dipsticks for rapid diagnosis of cholera caused by Vibrio cholerae O1 and O139 from rectal swabs
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DOI：
10.1128/jcm.41.8.3939-3941.2003
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发表时间：
2003-08-01
影响因子：
9.4
通讯作者：
Nair, GB
中科院分区：
文献类型：
--
作者：
Bhuiyan, NA;Qadri, F;Nair, GB
我们对最新研制的O1和0139型霍乱弧菌试纸进行了评价，这些试纸在碱性蛋白调水中浓缩4h后可以快速检测住院腹泻患者的直肠拭子中的O1和0139型霍乱弧菌。试纸的灵敏度和特异度分别在92%和91%以上。这种试纸代表了第一种已成功用于从直肠拭子中诊断霍乱的快速测试，这将极大地改善对霍乱的监测，特别是在偏远地区。
We evaluated the recently developed dipsticks for the rapid detection of Vibrio cholerae serotypes O1 and 0139 from rectal swabs of hospitalized diarrheal patients after enrichment for 4 h in alkaline peptone water. The sensitivity and specificity of the dipsticks were above 92 and 91%, respectively. The dipsticks represent the first rapid test which has been successfully used to diagnose cholera from rectal swabs, and this would immensely improve surveillance for cholera, especially in remote settings.