A sequential C-N, C-C bond-forming reaction:: Direct synthesis of α-amino acids from terminal alkynes
A sequential C-N, C-C bond-forming reaction:: Direct synthesis of α-amino acids from terminal alkynes
复制标题
DOI：
10.1055/s-2006-944211
复制
发表时间：
2006-11-03
期刊：
影响因子：
2
通讯作者：
Schafer, Laurel L.
中科院分区：
文献类型：
--
作者：
Lee, Alison V.;Schafer, Laurel L.
将催化氢胺化与Strecker反应相结合，以从末端炔一锅法合成α-氰基胺。该方法进一步应用于α-氨基酸和α-氨基酯的合成。
Catalytic hydroamination is combined with the Strecker reaction to yield a one-pot synthesis of alpha-cyanoamines from terminal alkynes. This methodology is further applied to the synthesis of alpha-amino acids and alpha-amino esters.