Mapping of short tandem repeat polymorphisms on human chromosome 3.
Mapping of short tandem repeat polymorphisms on human chromosome 3.
复制标题
人类 3 号染色体上短串联重复多态性的作图。
DOI：
10.1006/geno.1994.1030
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发表时间：
1994
期刊：
影响因子：
4.4
通讯作者：
Weber,JL
中科院分区：
文献类型：
--
作者：
Wilkie,PJ;Weber,JL
连锁分析被用来确定连续跨越186 cM的人类3号染色体的18个短串联重复序列多态性的地图位置。定位基于40个CEPH参考家族的基因分型。基因座排序为D3 S1252-D3 S1235-D3 S1234-D3 S1233-D3 S1254-D3 S1251-D3 S1215-RH 0-ACPP-D3 S1238-D3 S1206-D3 S196-D3 S1237-（D3 S1253，D3 S1439）-D3 S1243-D3 S1232-SST。在所有情况下，反对相邻标记倒位的几率为700：1或更好，除了在D3 S1253、D3 S1439处的标记对没有被任何重组体分离，因此不能排序。只有一个差距大于25厘米的性别平等的地图上观察。
Linkage analysis was used to determine map positions for 18 short tandem repeat polymorphisms that continuously span 186 cM of human chromosome 3. Mapping was based on the genotyping of 40 CEPH reference families. Loci order from pter-qter was D3S1252-D3S1235-D3S1234-D3S1233-D3S1254-D3S1251-D3S1215-RHO-ACPP-D3S1238-D3S1206-D3S196-D3S1237-(D3S1253,D3S1439)-D3S1243-D3S1232-SST. Odds against inversion of adjacent markers in all cases were 700:1 or better, except for the marker pair at D3S1253,D3S1439 that was not separated by any recombinants and therefore could not be ordered. Only one gap greater than 25 cM on the sex-equal map was observed.