Susceptibility Weighted Imaging at Ultra High Magnetic Field Strengths: Theoretical Considerations and Experimental Results
Susceptibility Weighted Imaging at Ultra High Magnetic Field Strengths: Theoretical Considerations and Experimental Results
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DOI：
10.1002/mrm.21754
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发表时间：
2008-11-01
影响因子：
3.3
通讯作者：
Reichenbach, Juergen R.
中科院分区：
文献类型：
--
作者：
Deistung, Andreas;Rauscher, Alexander;Reichenbach, Juergen R.
我们给出了磁化率加权成像(SWI)在7T下的数值模拟和实验结果，模拟了不同体素几何形状和成像参数下的幅度、相位和SWI对比度，得到了最佳静脉和周围组织对比度的回波时间为14毫秒。切片厚度是面内体素大小的两倍或更多，可获得最佳的血管可见性。体模和活体数据与模拟结果吻合得很好，7T时的血管轮廓优于较低的场强。复杂数据的阶段揭示了与相应的幅度图像互补的解剖细节。高场强磁化率加权成像是一种很有前途的成像技术，因为它对组织敏感度很高，比吸收率低，相位对B不均匀的敏感性可以忽略不计。《医学评论》60：1155-1168,2008。(C)2008年Wiley-Liss。
We present numerical simulations and experimental results for susceptibility weighted imaging (SWI) at 7 T. Magnitude, phase, and SWI contrast were simulated for different voxel geometries and imaging parameters, resulting in an echo time of 14 msec for optimum contrast between veins and surrounding tissue. Slice thickness of twice the in-plane voxel size or more resulted in optimum vessel visibility. Phantom and in vivo data are in very good agreement with the simulations and the delineation of vessels at 7 T was superior compared to lower field strengths. The phase of the complex data reveals anatomical details that are complementary to the corresponding magnitude images. Susceptibility weighted imaging at very high field strengths is a promising technique because of its high sensitivity to tissue susceptibility, its low specific absorption rate, and the phase's negligible sensitivity to B, inhomogeneities. Magn Reson Med 60:1155-1168, 2008. (C) 2008 Wiley-Liss.