Updates in Cervical Cancer Screening Guidelines, The Bethesda System for Reporting Cervical Cytology, and Clinical Management Recommendations.
Updates in Cervical Cancer Screening Guidelines, The Bethesda System for Reporting Cervical Cytology, and Clinical Management Recommendations.
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DOI：
10.14218/jctp.2023.00004
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发表时间：
2023-06
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在过去的几十年里，宫颈癌已经成为一个全球性的公共卫生问题。基于人群的早期癌症风险检测和预防方法，包括疫苗接种、细胞学筛查和人乳头瘤病毒（HPV）检测，配合临床管理，形成了完善的高质量宫颈癌控制实施体系，并革命性地提高了妇女的生活质量：（1）宫颈癌筛查实践的成功，（2）用于报告宫颈阴道细胞学的Bethesda系统的标准化，（3）提高对宫颈癌中HPV发病机制的理解，及（4）发展适当的管理方法已显著降低全球子宫颈癌的疾病负担。本范围审查旨在了解宫颈癌筛查和管理指南的演变，描述Bethesda宫颈细胞学报告系统，HPV疫苗和检测，并强调当前政策和实践的关键信息。
Over the past decades, cervical cancer has been a worldwide public health problem. Population-based early cancer risk detection and prevention approaches, including vaccination, cytology screening and human papilloma virus (HPV) detection, with the aligned clinical management, have formed a well-rounded high-quality implementation system for cervical cancer control, and revolutionarily improved the quality of life of women: (1) the success of cervical cancer screening practices, (2) standardization of The Bethesda system for reporting cervicovaginal cytology, (3) improvement in the understanding of HPV pathogenesis in cervical cancer, and (4) the development of appropriate management approaches have significantly decreased the disease burden of cervical cancer worldwide. This scoping review aimed to understand the evolvement of cervical cancer screening and management guidelines, describe the Bethesda cervical cytology reporting system, and HPV vaccines and tests, and highlight the key information of present policies and practices.