A DUAL EMBRYONIC ORIGIN FOR VERTEBRATE MECHANORECEPTORS
A DUAL EMBRYONIC ORIGIN FOR VERTEBRATE MECHANORECEPTORS
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DOI：
10.1126/science.8153631
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发表时间：
1994-04-15
期刊：
影响因子：
56.9
通讯作者：
MABEE, PM
中科院分区：
文献类型：
--
作者：
COLLAZO, A;FRASER, SE;MABEE, PM
神经乳突是鱼类和水生两栖动物侧线系统的机械感受器，以前被认为完全由胚胎表皮基板发育而来。利用命运映射技术表明，斑马鱼，暹罗斗鱼，非洲爪蟾的头部和身体的神经乳突也来自神经嵴。在脊椎动物的发育过程中，神经嵴从神经管迁移出来，形成大部分周围神经系统、色素细胞和头部的骨骼成分。本文所提供的数据表明，神经丘是来自神经嵴和表皮基板。
Neuromasts, the mechanoreceptors of the lateral line system of fishes and aquatic amphibians, have previously been thought to develop exclusively from embryonic epidermal placodes. Use of fate mapping techniques shows that neuromasts of the head and body of zebrafish, Siamese fighting fish, and Xenopus are also derived from neural crest. Neural crest migrates away from the neural tube in developing vertebrates to form much of the peripheral nervous system, pigment cells, and skeletal elements of the head. The data presented here demonstrate that neuromasts are derived from both neural crest and epidermal placodes.