Which Comorbid Conditions Should We Be Analyzing as Risk Factors for Healthcare-Associated Infections?
Which Comorbid Conditions Should We Be Analyzing as Risk Factors for Healthcare-Associated Infections?
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DOI：
10.1017/ice.2016.314
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发表时间：
2017-04-01
影响因子：
4.5
通讯作者：
Leekha, Surbhi
中科院分区：
文献类型：
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作者：
Harris, Anthony D.;Pineles, Lisa;Leekha, Surbhi
OBJECTIVE.根据专家共识，确定哪些合并症被认为与中心管相关血流感染（CLABSI）和泌尿系统部位感染（SSI）有因果关系。采用德尔菲法，对来自美国的9名传染病和感染控制专家进行了2轮调查。根据我们从Charlson和Elixhauser合并症指数中选择的成分，每位专家分别对CLABSI和SSI的35种不同的合并症进行了评分，从1（完全无关）到5（强相关），基于与结果的感知相关性。为了对每种共病疾病的因果关系分配专家共识，在第二轮结束时必须满足以下所有3个标准：（1）大多数（>50%）专家将疾病评级为3（有些相关）或更高，（2）四分位距（IQR）
OBJECTIVE. To determine which comorbid conditions are considered causally related to central-line associated bloodstream infection (CLABSI) and surgical-site infection (SSI) based on expert consensus.DESIGN. Using the Delphi method, we administered an iterative, 2-round survey to 9 infectious disease and infection control experts from the United States.METHODS. Based on our selection of components from the Charlson and Elixhauser comorbidity indices, 35 different comorbid conditions were rated from 1 (not at all related) to 5 (strongly related) by each expert separately for CLABSI and SSI, based on perceived relatedness to the outcome. To assign expert consensus on causal relatedness for each comorbid condition, all 3 of the following criteria had to be met at the end of the second round: (1) a majority (>50%) of experts rating the condition at 3 (somewhat related) or higher, (2) interquartile range (IQR)