Prognostic implication of frailty and depressive symptoms in an outpatient population with heart failure
Prognostic implication of frailty and depressive symptoms in an outpatient population with heart failure
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DOI：
10.1016/s1885-5857(08)60231-5
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发表时间：
2008-08-01
影响因子：
5.9
通讯作者：
Valle, Vicente
中科院分区：
文献类型：
--
作者：
Lupon, Josep;Gonzalez, Beatriz;Valle, Vicente
引言和目标。心力衰竭患者有高度的虚弱和依赖性。我们的目的是确定衰弱和抑郁症状对1年死亡率和1年随访期间心力衰竭住院率的影响。所有患者都进行了老年评估，并确定了虚弱和抑郁症状。该研究纳入了622例患者（72.5%为男性；中位年龄为68岁；92%为纽约心脏协会11级或111级；中位射血分数为30%）。随访期间，60例（9.5%）患者死亡，101例（16.2%）患者因心力衰竭住院。总体而言，39.9%的患者表现出虚弱，25.2%的患者表现出抑郁症状。1年死亡率与虚弱之间存在显著相关性(16.9% vs. 4.8%； P
Introduction and objectives. Heart failure patients have high levels of frailty and dependence. Our aim was to determine the impact of frailty and depressive symptoms on the 1-year mortality rate and the rate of hospitalization for heart failure during a follow-up period of 1 year.Methods. All patients underwent geriatric evaluation, and frailty and depressive symptoms were identified. The study included 622 patients (72.5% male; median age, 68 years; 92% in New York Heart Association class 11 or 111; and median ejection fraction, 30%).Results. During follow-up, 60 patients (9.5%) died and 101 (16.2%) were hospitalized for heart failure. Overall, 39.9% of patients exhibited frailty, while 25.2% had depressive symptoms. There were significant associations between mortality at 1 year and the presence of frailty (16.9% vs. 4.8%; P