Catalytic Janus Motors on Microfluidic Chip: Deterministic Motion for Targeted Cargo Delivery
Catalytic Janus Motors on Microfluidic Chip: Deterministic Motion for Targeted Cargo Delivery
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DOI：
10.1021/nn300413p
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发表时间：
2012-04-01
期刊：
影响因子：
17.1
通讯作者：
Schmidt, Oliver G.
中科院分区：
文献类型：
--
作者：
Baraban, Larysa;Makarov, Denys;Schmidt, Oliver G.
我们制造了自供电的胶体Janus马达，结合催化和磁性帽结构，并展示了它们在微流控芯片上操纵（上传，运输，交付）和分选微物体的性能。Janus电机的特定磁特性由沿盖的主对称轴沿着排列磁矩的多层薄膜提供。这种独特的性质允许确定性运动的Janus粒子在一个大规模的引导时，在外部磁场。观察到的运动方向控制与胶体Janus电机的广泛功能相结合，在概念上为靶向递送物质开辟了一条简单的路线，这与化学、生物学和医学领域相关。
We fabricated self-powered colloidal Janus motors combining catalytic and magnetic cap structures, and demonstrated their performance for manipulation (uploading, transportation, delivery) and sorting of microobjects on microfluidic chips. The specific magnetic properties of the Janus motors are provided by ultrathin multilayer films that are designed to align the magnetic moment along the main symmetry axis of the cap. This unique property allows a deterministic motion of the Janus particles at a large scale when guided in an external magnetic field. The observed directional control of the motion combined with extensive functionality of the colloidal Janus motors conceptually opens a straightforward route for targeted delivery of species, which are relevant in the field of chemistry, biology, and medicine.