Extracytoplasmic Function σ Factors Regulate Expression of the Bacillus subtilis yabE Gene via a cis-Acting Antisense RNA

Extracytoplasmic Function σ Factors Regulate Expression of the Bacillus subtilis yabE Gene via a cis-Acting Antisense RNA
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DOI:
10.1128/jb.01530-08
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发表时间:
2009-02-01
影响因子:
3.2
通讯作者:
Helmann, John D.
Helmann, John D.
中科院分区:
生物学3区
文献类型:
--
作者:
Eiamphungporn, Warawan;Helmann, John D.

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枯草芽孢杆菌Yabe编码一个预测的复苏促进因子/稳定期存活(RPF/SPS)自溶素家族。在这里,我们证明了Yabe是由顺式作用的反义RNA负调节的,而反义RNA又受两个胞质外功能sigma因子的调节:Sigma(X)和Sigma(M)。
Bacillus subtilis yabE encodes a predicted resuscitation-promoting factor/stationary-phase survival (Rpf/Sps) family autolysin. Here, we demonstrate that yabE is negatively regulated by a cis-acting antisense RNA which, in turn, is regulated by two extracytoplasmic function sigma factors: sigma(X) and sigma(M).