Methionine restriction and antitumor immunity.
Methionine restriction and antitumor immunity.
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蛋氨酸限制和抗肿瘤免疫。
DOI:
10.1016/j.trecan.2023.07.008
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发表时间:
2023
期刊:
影响因子:
18.4
通讯作者:
Locasale,JasonW
中科院分区:
文献类型:
--
作者:
Wei,Fangchao;Locasale,JasonW
Fang et al. recently reported inCancer Cellthat methionine restriction increases antitumor immunity by enhancing cyclic GMP-AMP synthase (cGAS) activity and promoting its dissociation from chromatin. This finding identifies a potential strategy to target cGAS demethylation in cancer therapy by altering methionine metabolism.
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发表时间:
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期刊:
Science (New York, N.Y.)
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