Stiff-persons' syndrome associated with thymoma and subsequent myasthenia gravis
Stiff-persons' syndrome associated with thymoma and subsequent myasthenia gravis
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DOI：
10.1002/(sici)1097-4598(199704)20:4
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发表时间：
1997-04-01
期刊：
影响因子：
3.4
通讯作者：
Oh, SJ
中科院分区：
文献类型：
--
作者：
Nicholas, AP;Chatterjee, A;Oh, SJ
我们报告的第一例僵硬的人（人）综合征的设置组织学证实胸腺瘤。全身麻醉下肌肉活动过度消失，在胸腺切除术和三个疗程的静脉注射免疫球蛋白后，僵硬症状消失。胸腺切除术后，患者出现眼部重症肌无力，随后自行消退。我们建议胸腺瘤应寻求与神经肌肉多动综合征的情况下。重症肌无力可能在这些情况下随后发展。(C)John Wiley & Sons，Inc.
We report the first case of stiff-persons' (-man) syndrome in the setting of a histologically proven thymoma. Muscular hyperactivity was abolished under general anesthesia and the symptoms of stiffness resolved after thymectomy and three courses of intravenous immunoglobulins. After thymectomy, the patient developed ocular myasthenia gravis which later resolved spontaneously. We suggest that thymoma be sought for in cases with neuromuscular hyperactivity syndromes. Myasthenia gravis may develop subsequently in these cases. (C) 1997 John Wiley & Sons, Inc.