Urinary function in elderly people with and without leukoaraiosis: relation to cognitive and gait function
Urinary function in elderly people with and without leukoaraiosis: relation to cognitive and gait function
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DOI：
10.1136/jnnp.67.5.658
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发表时间：
1999-11-01
影响因子：
11
通讯作者：
Yamanishi, T
中科院分区：
文献类型：
--
作者：
Sakakibara, R;Hattori, T;Yamanishi, T
目的探讨有无白质病变（白质病变）的老年人尿功能与认知和步态功能的关系。方法：研究对象63名，平均年龄73岁（62 ~ 86岁）。排除脑干卒中或大半球病变的受试者。自旋回波1.5 T MRI图像根据白质病变的严重程度从0到4分级。通过详细的问卷调查评估了泌尿功能，并对33名受试者进行了尿动力学研究，包括排尿后残留物测量、膀胱水测术和括约肌肌电图。还进行了迷你精神状态检查（MMSE）和步态检查，并与泌尿功能进行了比较。结果：尿动力学研究显示，1-4级白质病变患者出现逼尿肌反射过度的比例（82%）高于0级白质病变患者（9%）
Objectives-To investigate urinary function in the elderly with and without white matter lesion (leukoaraiosis) in relation to cognitive and gait function.Methods-Sixty three subjects were examined, with mean age 73 (range 62 to 86 years). Subjects with brainstem stroke or with large hemispheric lesions were excluded. Spin echo 1.5 T MRI images were graded from 0 to 4 for severity of white matter lesions. Urinary function was assessed by detailed questionnaire and urodynamic studies were performed in 33 of the subjects, including measurement of postmicturition residuals, water cystometry, and sphincter EMG. A mini mental state examination (MMSE) and examination of gait was also performed and compared with urinary function.Results-Urodynamic studies showed subjects with grade 1-4 white matter lesions to have detrusor hyperreflexia more commonly (82%) than those with grade 0 white matter lesions (9%) (p