Gold(I)‐Catalyzed Diastereo‐ and Enantioselective Synthesis of Polysubstituted Pyrrolo[3,4‐d][1,2]oxazines
Gold(I)‐Catalyzed Diastereo‐ and Enantioselective Synthesis of Polysubstituted Pyrrolo[3,4‐d][1,2]oxazines
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DOI：
10.1002/cjoc.201700575
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发表时间：
2018-06
影响因子：
5.4
通讯作者：
Mei-Na Zhang;Xiaoyu Di;Mingrui Zhang;Junliang Zhang
中科院分区：
文献类型：
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作者：
Mei-Na Zhang;Xiaoyu Di;Mingrui Zhang;Junliang Zhang
A gold(I)‐catalyzed highly diastereo‐ and enantioselective intermolecular cycloaddition of oxime ethers with nitrones under mild conditions was developed, which provides an facile access to optically pure highly substituted pyrrolo[3,4‐d][1,2]oxazines. The salient features of this reaction include general substrate scope, high efficiency, high enantioselectivity, readily available starting materials, and the use of commercially available ligand.
